Professor Sarah E. Reisman of the California Institute of Technology (Caltech) will use a $900,000 Project Grant from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) to develop new catalytic reactions for the synthesis of natural products. Over three years from July 2022 to June 2025, Reisman and her team will focus on inventing, testing, and refining new carbon-carbon bond forming reactions through two natural product synthesis projects. The...
The National Science Foundation awarded a $500,000 Project Grant to the California Institute of Technology under the Mathematical and Physical Sciences federal grant program (CFDA 47.049) to support the development of new transition metal-catalyzed reaction methods for synthesizing alkaloids with anticancer properties. Professor Brian Stoltz and his team at Caltech will utilize palladium-catalyzed reactions to rapidly construct the complex molecular frameworks of targeted marine-derived chemical...
This National Science Foundation (NSF) award, under the Mathematical and Physical Sciences (CFDA 47.049) program, provides $575,000 to the University of California, Davis (UC Davis) to study the development of new silicon-based molecules and their use as catalysts for efficient organic synthesis and renewable polymer production. The 3-year project, led by Professor Annaliese Franz, aims to design innovative multi-functional silanol ligands with unique properties that can enable the creation of...
This $650,000 Project Grant awarded by the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) funds an industrial-academic collaboration between Princeton University and the Merck Catalysis Laboratory. The goal is to develop new sustainable catalytic methods for the large-scale synthesis of pharmaceutical drugs using earth-abundant metals like iron, cobalt, and nickel instead of rare precious metals. The research aims to identify viable catalytic...
Through a $497,704 Project Grant award from the National Science Foundation's Chemical Catalysis program (CFDA 47.049 Mathematical and Physical Sciences), Professor Ming-Yu Ngai of Purdue University is conducting research to develop new sustainable catalytic processes leveraging first-row transition metals. The project aims to expand understanding of radical migration mechanisms and enable site- and stereoselective functionalization of carbohydrates and other small molecule building blocks....
The National Science Foundation (NSF) awarded a $600,000 Project Grant under the Mathematical and Physical Sciences Federal Grant Program (CFDA 47.049) to the Massachusetts Institute of Technology (MIT) for a project titled "Design and Application of Highly Reactive Redox-Active Organophosphorus Catalysts." The project, led by Professor Alexander Radosevich, aims to develop new inexpensive chemical catalysts composed of earth-abundant elements like iron and phosphorus that can enable...
This Project Grant from the National Science Foundation Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), provides $221,000 to Professor Karl Scheidt of Northwestern University to develop new catalytic transformations for accessing saturated heterocycles through August 1, 2022 to July 31, 2023. The funding supports research aiming to facilitate access to chiral heterocyclic compounds through new bond-forming reactions, enabling the efficient and...
This Project Grant award from the National Science Foundation (NSF) Mathematical and Physical Sciences program (CFDA 47.049) provides $211,772 to Professor Liela Romero at Baylor University to develop new strategies for chemical synthesis using early transition metal catalysts. The key objectives are to: 1) advance the fundamental chemistry of Group IV transition metals, 2) expand the utility of metal hydride catalysis, and 3) create innovative synthetic tools. The grant supports research to...
This Project Grant award of $900,000.00 from the National Science Foundation's (NSF) Division of Chemistry, under the Mathematical and Physical Sciences Federal Grant Program (CFDA 47.049), supports research by Professors Houk and Tang of the University of California, Los Angeles (UCLA) to study the development of a new class of enzymes called "pericyclases." The researchers aim to characterize the mechanisms by which these enzymes catalyze natural product biosynthetic reactions,...
This $200,000 Project Grant award from the National Science Foundation (NSF) Mathematical and Physical Sciences (CFDA 47.049) program will support a postdoctoral research fellowship under the mentorship of Dr. Sarah Reisman at the California Institute of Technology (Caltech). The fellowship, awarded to Dr. Kristen Gardner, aims to develop a novel dual ligand nickel-catalyzed system for enantioselective cross-coupling reactions using unactivated alkyl chlorides. This research seeks to address...