Project Grant 2453374

Award Date 7/1/25
Completion Date 6/30/28
Dollars Obligated $600K
Federal Grant Program
47.049
Assistance Type
Project Grant
Place of Performance
Rochester, NY 14611, USA
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This Project Grant award, provided by the National Science Foundation's (NSF) Division of Chemistry under the Mathematical and Physical Sciences Federal Grant Program (CFDA 47.049), is supporting Professor Alison Frontier of the University of Rochester in the study of anomalous forms of known cyclization reactions. The $600,000 award, spanning July 1, 2025 to June 30, 2028, focuses on three key research projects:

  1. Exploring the interface between electrocyclic and ionic reactivity to characterize a group of unusual pentannulation reactions.

  2. Developing synthetically useful higher-order cationic electrocyclizations to expand the boundaries of electrocyclic reactivity.

  3. Studying nonlinear polyene cyclizations to enable the synthesis of highly functionalized, topologically complex heterocycles.

Additionally, the award supports ongoing maintenance and improvements to Professor Frontier's "Not Voodoo" educational website, which serves as a resource for organic chemistry students and researchers. No sub-awards are planned under this grant.

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