This $663,306 Project Grant award from the National Institute of General Medical Sciences (CFDA 93.859 Biomedical Research and Research Training) is funding research to understand how environmental factors across land-sea ecosystems shape the ecology and transmission of virulent parasites, specifically Toxoplasma gondii and Sarcocystis neurona, that infect southern sea otters. The 4-year project, with a start date of Sep 1, 2024, aims to generate new datasets and develop an integrative...
This federal Project Grant award, provided by the National Science Foundation (NSF) Biological Sciences (CFDA 47.074) program, will fund a research project titled "EXPERIMENTAL EVALUATION OF DISPERSAL AS A PARASITE AVOIDANCE STRATEGY". The primary goal is to advance the understanding of how host strategies, specifically dispersal behavior, can evolve to avoid contracting infectious diseases from parasites. The $1,500,000 award, spanning 5 years from Sep 1, 2025 to Aug 31, 2030, will...
This $563,513 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research to investigate the patterning, growth, and maturation of the cortical microtubules in the Toxoplasma parasite. The research aims to uncover the basic mechanisms by which this unicellular parasite, which causes diseases like toxoplasmosis, constructs its complex cytoskeletal framework. The findings...
This $696,447 federal Project Grant award, administered by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074), will stabilize, curate, and provide digital access to approximately 128,000 specimens of parasites collected from a wide range of vertebrate hosts over the past 80 years. The award to the University of Connecticut aims to preserve these irreplaceable historical parasite collections, update host identifications, and make the data publicly available through...
This $196,163 federal Project Grant award from the National Science Foundation (NSF) under the Mathematical and Physical Sciences program (CFDA 47.049) is funding a collaborative research project on developing advanced mathematical models to improve understanding and management of schistosomiasis transmission dynamics. The project is a collaboration between the University of Florida, University of Georgia, and University of Massachusetts, and aims to create innovative hybrid...
The University of California, Merced was awarded a $269,054 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The grant, titled "Defining Novel Susceptibility Mechanisms to Low Virulence Toxoplasma Gondii Strains Using the Collaborative Cross and Parasite Genetics," aims to leverage the Collaborative Cross mouse panel and parasite genetics to dissect the mechanisms that...
This Project Grant award of $792,845 from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) supports research to georeference, curate, and augment the largest global host-helminth (parasitic worm) database. The researchers at the University of South Carolina will clean and enhance this database, which currently contains over 250,000 interactions between helminth parasites and their hosts, to improve its accuracy and accessibility for researchers studying...
This $1,108,345 federal Project Grant award, funded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074), supports research to characterize the evolutionary transition of host-microbe interactions from commensal symbionts to blood parasites in apicomplexan organisms, which include the parasites that cause malaria. The project, led by the University of Rhode Island, will use advanced microscopy and genomics to compare the cellular invasion machinery between...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to characterize human-animal contact networks and improve zoonotic disease modeling. The $720,456 award, with a performance period from September 2024 to August 2029, will be used to collect empirical data on human-livestock contact networks in Mongolia, develop generative network models, and integrate these...
This Project Grant award of $176,537 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) will support research to investigate the role of reactive oxygen species (ROS) in controlling acute Toxoplasma gondii infection. The key objectives are to: 1) determine the cellular events and receptors involved in inducing ROS production in T. gondii-infected neutrophils, 2) identify whether ROS is mediated through...
This $85,056 federal Project Grant award from the National Science Foundation's Integrative Activities (CFDA 47.083) program aims to advance research on the zoonotic parasite Toxoplasma gondii and its transmission at the human-animal-environment interface. The grant will establish an international network-of-networks to facilitate collaborative research, standardize field and lab methods, provide training opportunities, and harmonize data management approaches. Key activities include an in-person workshop, postdoctoral and graduate student exchanges, and developing shared tools and protocols across network partners. The University of Nebraska is the prime awardee, with sub-awards planned for the University of California, Davis and the University of Pennsylvania to contribute their research expertise. This project seeks to enhance public and animal health, wildlife conservation, and STEM workforce development related to understanding global patterns of this globally-distributed parasite.