Project Grant 2448256
- The National Science Foundation (NSF) awarded a $800,000 Project Grant under the Biological Sciences program (CFDA 47.074) to The Washington University's Office of Sponsored Research Services Division. The 3-year project aims to investigate the metabolic cooperation between a phototrophic bacterium and a methanogenic archaeon, and how this "syntrophic" interaction influences methane production and the nitrogen cycle in anoxic environments. The research will shed light on how these...
- The National Science Foundation (NSF) Biological Sciences Federal Grant Program (CFDA 47.074) awarded a $819,654 Project Grant to the University of North Texas on February 1, 2025. The grant supports research to advance the understanding of methanotrophic bacteria metabolism and physiology. The project aims to leverage recent genetic tools and CRISPR interference techniques to further define the role of CO2 and the Ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) in the metabolism and...
- This Project Grant award from the National Science Foundation's Engineering program (CFDA 47.041) provides $575,765 to Northeastern University to conduct research focused on "metabolic 'doping' to enhance production of biochemicals from sustainable C1 feedstocks." The key objectives are to understand the regulation of carbon metabolism in acetogens, bacteria that can grow on single-carbon (C1) molecules, and to genetically engineer these organisms to become more effective producers...
- This $700,000 Project Grant award from the National Science Foundation's (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program supports a research project at Arizona State University (ASU) to "Elucidate, Understand, and Leverage 'Covert' Metabolic Interactions in Synthetic Microbial Communities". The project aims to reveal valuable, previously unknown microbial interactions that could be leveraged to engineer microbial communities for applications in food production, high-value...
- The National Science Foundation awarded a $716,898 Project Grant to the University of North Texas under the Biological Sciences federal grant program (CFDA 47.074) to develop advanced biocatalyst tools and resources to enable biogas-based biomanufacturing from August 15, 2022 to July 31, 2025. Specifically, the University of North Texas will utilize genetic engineering and metabolic modeling to advance methanotroph-based biotechnologies for the sequestration and utilization of methane and carbon...
- This $325,937 Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports collaborative research at Michigan State University (MSU) to interrogate the interconnection of structural and metabolic dynamics of evolutionarily distinct bacterial microcompartments. The project aims to study the impact of geometry and permeability of microcompartments in two distantly related bacteria under varying realistic environments, with the goal of gaining...
- This $360,000 project grant awarded by the National Science Foundation's (NSF) Engineering program (CFDA 47.041) to Temple University supports research to develop synthetic microbial communities capable of robust electro-methanogenesis. The goal is to improve the process of converting organic waste into renewable biogas by leveraging microorganisms that can use electricity as an energy source. The research aims to build resilient electro-methanogenic communities, quantify the drivers of...
- This National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) Project Grant award of $900,000.00 to Colorado State University (CSU) aims to develop a novel microbiome modeling platform. The platform will integrate omics data, thermodynamics principles, metabolic models, and artificial intelligence to unravel the metabolism, interactions, and evolution of microbiomes. This research will be applied to address specific questions regarding the microbiome of a "rewired...
- The National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program has awarded Virginia Polytechnic Institute & State University (Virginia Tech) a $300,000 Project Grant to elucidate the proteins involved in trafficking and delivering nickel to nickel-dependent enzymes in methanogenic archaea. The project aims to define the nickel homeostasis mechanisms, including nickel uptake, storage/export, and enzyme assembly, in these microorganisms that produce methane as...
- This National Science Foundation Project Grant of $581,720 awarded under the Biological Sciences program (CFDA 47.074) supports research to improve understanding of post-thaw permafrost microbiomes. The awardee, University of New Hampshire, will conduct a series of integrated research, education, and broader impacts activities from April 1, 2022 to March 31, 2027. Specifically, the university will synthesize DNA sequence data on post-thaw microbiomes, use ecological modeling to assess...
This Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) provides $1,087,895.00 to the University of Nebraska to identify and characterize spatially coupled biochemical processes in methanogenic archaea. The research aims to investigate how the enzymes used by these microbes work together to efficiently convert low-energy substrates like acetate and methanol into the high-energy fuel methane gas. By revealing the enzyme interactions within methanogenic archaea cells, the project will improve understanding of how these microbes function in various natural environments and generate knowledge that could be used to increase the supply of renewable methane fuel. The award supports recruiting and training undergraduate, graduate, and postdoctoral students in anaerobic microbial physiology, molecular biology, and redox biochemistry. The project period runs from September 1, 2025 to August 31, 2028.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.1m | 8/14/25 |