Project Grant 2447992
- This Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) provides $441,848 to the University of California, Santa Barbara to conduct research on the fundamental science of "complex coacervates", which are microscopic droplets formed from charged polymers. The research aims to develop a mechanistic understanding of how these materials form and their unique properties, such as the ability to encapsulate and deliver...
- This National Science Foundation project grant of $500,000 will fund research at the University of California, Santa Barbara to study the assembly, disassembly, and mechanics of porous colloidal vesicles from April 15, 2023 to March 31, 2026. The research aims to advance understanding of fundamental processes involved in vesicle formation that are relevant across fields including physics, biology, engineering, and materials science. The university researchers will utilize state-of-the-art...
- This Project Grant award from the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) program provides $156,400.00 to the University of Massachusetts (UMass) to conduct research on engineering selective membranes from lipid-polyelectrolyte complexes. The objective is to harness biology-inspired principles to create high-precision synthetic membranes for applications like water purification and pharmaceutical processing, while avoiding the use of toxic...
- This Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) provides $364,550 to Amherst College to study the rules for designing active DNA materials using condensing agents. The key objectives are to investigate how condensing agents can bend, loop, and reconfigure DNA in order to impart desirable properties like decreased size, increased stability, and altered electrical conductivity. The research will be conducted entirely by...
- This federal Project Grant award from the National Science Foundation (CFDA 47.049 - Mathematical and Physical Sciences) provides $620,209 to Northeastern University to develop a platform for rational design of polymer-based oligonucleotide delivery vehicles using digital bottlebrush architectures. The key goals are to: (1) synthesize and characterize a library of ribose-based digital bottlebrush polymers with controlled hydrophobicity and charge, and (2) study their biodistribution,...
- This $500,000 federal Project Grant award, funded by the National Science Foundation's (NSF) Mathematical and Physical Sciences Program (CFDA 47.049), supports research to develop a mathematical framework for understanding how porous materials can enhance the efficiency of viral transduction in engineered cell therapies. The award was granted to North Carolina State University (UEI: U3NVH931QJJ3) and will run from September 1, 2025 to August 31, 2028. The key objective of this project is to...
- This $447,000 Project Grant from the National Science Foundation's Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), will support research at Haverford College from December 2022 through February 2026. The research team, led by Dr. Louise Charkoudian, will investigate type II polyketide biosynthetic enzyme assemblies across bacterial species to leverage their capabilities for sustainable chemical production. Undergraduate students will gain research...
- This $595,829 federal project grant was awarded by the National Science Foundation's Mathematical and Physical Sciences (CFDA 47.049) program to The Trustees of the University of Pennsylvania to fund research on the propulsion of synthetic cell-like capsules driven by biochemical catalysis. The key objectives are to: Measure the motility of single enzyme-functionalized capsules across a range of enzyme-substrate systems and quantify the directional motion of asymmetric "Janus" capsules...
- The National Science Foundation (NSF) awarded a $550,000 Project Grant to Colorado State University (CSU) under the CFDA 47.049 Mathematical and Physical Sciences program. The grant supports CSU's Dr. Margarita Herrera-Alonso in exploring the formation of gene-carrying nanoparticles from synthetic macromolecules with complex architectures. The goal is to establish design principles for polymer/gene assemblies that can enhance the stability and therapeutic efficacy of gene therapy delivery...
- This $208,784 federal Project Grant award from the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049) supports a collaborative research project to study the emergent dynamics and scaling laws of bioinspired lipid membranes. The University of Arizona, as the primary awardee, will integrate experimental methods such as neutron spectroscopy, NMR, and flicker spectroscopy with molecular dynamics simulations. This integrated approach aims to establish the...
This Project Grant award from the National Science Foundation's Mathematical and Physical Sciences Program (CFDA 47.049) will support research at Ursinus College to characterize novel ionizable amphiphilic Janus dendrimer-based vesicles and evaluate their potential for delivering nucleic acid therapeutics. The $230,784 award, active from August 1, 2025 to July 31, 2028, will fund studies to understand how the physicochemical properties of these Janus dendrimer vesicles impact their interactions with biological systems and ability to encapsulate and deliver nucleic acids to cells. This work aims to advance the development of effective biomaterial-based delivery systems for nucleic acid therapies, with potential applications in areas like the COVID-19 mRNA vaccine. The project will also provide valuable undergraduate research experiences and help establish a new biophysical chemistry mini-course at Ursinus College.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $230.8k | 7/16/25 |