This National Science Foundation (NSF) Project Grant award, funded under the Engineering program (CFDA 47.041), provides $319,574 to Iowa State University to develop a model for understanding how traveling waves in the brain drive interstitial fluid flow in the porous brain cortex. The overarching goal is to advance the fields of porous media flows, biofluid dynamics, and neuroscience, which could lead to the development of therapeutic strategies against neurological disorders. Key objectives include: 1) modeling interstitial fluid dynamics using volume-averaging techniques, 2) quantifying interstitial fluid flow driven by traveling waves, and 3) analyzing the influence of wave properties on fluid flow in healthy and diseased brains. The award period is from April 15, 2025 to March 31, 2028, and the research will involve mentoring graduate and undergraduate students, creating a course on neuro-fluid dynamics, and organizing a workshop for high school students.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $319.6k | 6/13/25 |