Project Grant 2232598
- This Project Grant award from the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049) will leverage artificial intelligence velocimetry to measure cerebrospinal fluid flow in the brain. The $299,999 award to the University of Rochester will address key knowledge gaps about how the brain's waste clearance system functions, especially in aging and disease states like Alzheimer's. The 3-year project (9/1/2025 - 8/31/2028) will use this novel AI-based imaging...
- This federal Project Grant award of $319,574, provided by the National Science Foundation's (NSF) Engineering program (CFDA 47.041), will support Iowa State University in developing a swelling-porous media model to understand how traveling waves in the brain drive interstitial fluid flow during physiological and acute neurological conditions. The key objectives of this research project are to: 1) model interstitial fluid dynamics in the porous brain cortex using a volume-averaging technique...
- This two-year, $200,000 project grant from the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems supports research at Michigan Technological University under the NSF Engineering program (CFDA 47.041). The university will develop a non-Newtonian blood analog solution and assess its impact on flow properties in aortic root models under pulsatile conditions. Specifically, the grantee will prepare and test the rheological properties of a...
- The National Science Foundation (NSF) has awarded a $266,856 Project Grant to the San Diego State University Research Foundation under the NSF Engineering program (CFDA 47.041) for the period of May 1, 2024 to April 30, 2027. The grant aims to investigate the relationship between acoustically generated force fields, deformable vessel wall mechanics, and bubble oscillation dynamics to understand how microbubble clusters can be used to navigate through blood vessels. The research team will...
- This National Science Foundation Project Grant, awarded under the Engineering program (CFDA 47.041), provides $206,132 to Louisiana State University to conduct fundamental research on the high strain rate mechanics of the human brain. The research aims to develop advanced computational models and experimental techniques to better understand the complex mechanical behavior of the living human brain under extreme loading conditions, such as those encountered during traumatic brain injuries. The...
- The National Science Foundation (NSF) awarded The Johns Hopkins University a 3-year, $274,297 Project Grant under the Engineering program (CFDA 47.041) to conduct collaborative research on the extreme mechanics of the human brain. The research aims to generate insights into how the living human brain responds to large and rapid loading, which is critical for developing models to predict traumatic brain injury and designing safer protective equipment. The project will combine high-rate mechanical...
- This four-year, $1.1 million Project Grant from the National Science Foundation's Computer and Information Science and Engineering program will fund the development of physics-informed machine learning techniques to analyze dynamic blood flow from static subtraction computed tomographic angiography imaging. The University of Wisconsin-Milwaukee will train graduate students in deep learning methods and engage undergraduates and local high school students, particularly those from...
- The University of Wisconsin-Milwaukee received a $298,509 project grant award from the National Science Foundation Division of Electrical, Communications and Cyber Systems under the Engineering federal grant program (CFDA 47.041). The three-year award will support research to enhance 4D-flow MRI through deep data assimilation for hemodynamic analysis of cardiovascular flows. Specifically, the University will collaborate on developing enhanced medical imaging techniques using data assimilation...
- The National Science Foundation awarded a $595,104 Project Grant to the University of Maryland, College Park under the Engineering program (CFDA 47.041) to support research on integrated experimental and computational models of brain microvascular endothelial cell glucose metabolism and transport from September 1, 2022 to August 31, 2025. The award will fund the development of new experimental and computational models to study how decreased membrane cholesterol affects brain microvascular...
- The National Science Foundation (NSF) Engineering program (CFDA 47.041) awarded a $500,000 project grant to Florida State University (FSU) for the "Locomotion Dynamics in Yield Stress Fluids" research project. The award will run from September 1, 2025 to August 31, 2028. The project aims to combine innovative experiments using a helical corkscrew and self-propelled robotic swimmer with advanced 3D simulations to uncover the physical principles governing locomotion in gel-like...
This National Science Foundation project grant award of $222,804 provides funding to Western Michigan University from October 1, 2022 through September 30, 2024 to explore impacts of head motion on cerebrospinal fluid dynamics using simulation and real-time medical imaging. The NSF Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded the funding under the Engineering (47.041) federal grant program. The awardee will develop a medical image-based approach to examine the effects of head motion on cerebrospinal fluid dynamics in the brain. Using advanced in vivo magnetic resonance imaging technology, the project will track unsteady cerebrospinal fluid flow in a moving brain and use computational fluid dynamics simulation for in-depth investigation. Anatomically and physiologically correct brain modeling based on MRI images will be developed. Simulation results and MRI data will be examined to reveal crucial fluid dynamics such as how flow disturbances generated by head motions grow and decay and how convective mixing of cerebrospinal fluid varies with head motions. This work is expected to yield fundamental understanding of ventricular cerebrospinal flow dynamics responses to head motions.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $222.8k | 8/8/22 |
GrantNumber | Description | Subgrantee | Prime Award | Dollars Obligated | Updated At |
|---|---|---|---|---|---|
220160JUNTENDOS | Juntendo University | Project Grant 2232598 | $14.6k | 4/12/24 |