This National Science Foundation (NSF) Engineering program (CFDA 47.041) project grant, awarded to Worcester Polytechnic Institute (WPI), will develop in vitro models to study fibrosis progression and regression across different tissue types, including the pancreas, skin, and uterine fibroids. The $629,998 award, running from June 1, 2025 to May 31, 2030, will enable WPI to engineer these tissue-specific models to investigate how extracellular matrix properties, cellular composition, and biochemical interactions influence fibrotic processes. The project aims to advance understanding of fibrosis at the cellular level and identify potential targets for future therapies. In addition, the award includes STEM education and community outreach components focused on expanding participation and improving medical literacy. This comprehensive effort leverages WPI's expertise in biomaterials, bioengineering, and interdisciplinary research to address critical knowledge gaps around fibrosis, a leading contributor to mortality in industrialized nations.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $630.0k | 6/11/25 |