The University of Texas at Arlington (UTA) has been awarded a National Science Foundation (NSF) Project Grant under the Biological Sciences program (CFDA 47.074) for the project "UNCOVERING SMALL RNA AND CHROMATIN MODIFYING PATHWAY INTERACTIONS THAT REGULATE TRANSCRIPTOME HOMEOSTASIS". The $171,061 grant, awarded on February 15, 2025, aims to advance the understanding of how RNA interference (RNAi) and chromatin modifying pathways collaborate to maintain appropriate gene regulation during environmental stress, using the C. elegans germline as a model system. The research will provide insights into the epigenetic and transcriptional landscape of germ cells, the mechanisms that balance these gene regulatory pathways, and the impacts of genetic and environmental perturbations. The project will also engage undergraduate and graduate researchers through paid research opportunities, interdisciplinary training, and the establishment of a regional scientific seminar series and conference. No subawards are planned under this grant.
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