The National Science Foundation (NSF) awarded a $499,957 Project Grant under the Biological Sciences program (CFDA 47.074) to President and Fellows of Harvard College to implement the "Design: Culture Change - Building a Relational and Inclusive Discipline through Genetics Engagement (CC-BRIDGE)" project. This two-year pilot aims to examine the role of public engagement in fostering a more diverse, inclusive, and equitable culture within the field of genetics. The project will...
The National Science Foundation awarded a $514,999 Project Grant to the President and Fellows of Harvard College from February 15, 2021 through January 31, 2024 under the Biological Sciences program (CFDA 47.074). The grant funds collaborative research to design a minimized genome cyanobacterial chassis for efficient bioproduction. The Biological Sciences program aims to promote advancement in the biological sciences and strengthen the national scientific enterprise through increasing...
This $1,100,000 Project Grant award from the National Science Foundation (CFDA 47.074 - Biological Sciences) to President and Fellows of Harvard College aims to advance the understanding of plasmid evolution within bacterial cells. The research will develop novel experimental tools and techniques to precisely measure intracellular plasmid competition and investigate the mechanisms and evolutionary dynamics of these important mobile genetic elements. The project will also create educational...
This National Science Foundation (NSF) Biological Sciences program grant awarded to New York University (NYU) is titled "EAGER: A GENOME WIDE HDR ENHANCEMENT SCREEN IN MAIZE." The $300,000 award, made on May 1, 2024, funds a 2-year project to develop an efficient method for using CRISPR gene editing technology to transfer stress-tolerant traits between plant varieties. The project aims to identify genes in maize (corn) that can enhance the efficiency of CRISPR-mediated...
This three-year Project Grant from the National Science Foundation, totaling $1,996,695, will support research to expand the functions of a 57 codon recoded E. coli genome. The award was made on August 1, 2021 to President and Fellows of Harvard College, with performance taking place in Cambridge, Massachusetts. The research aims to promote progress in the biological sciences by increasing scientific knowledge and enhancing understanding of major problems, as outlined in the Biological...
The National Science Foundation Division of Integrative Organismal Systems awarded a $314,715 Project Grant to President And Fellows Of Harvard College from September 1, 2021 to August 31, 2024. The grant supports collaborative research titled "EDGE FGT: Transformation and Genomic Resources to Advance Diverse, Emerging Model Angiosperms" under the Biological Sciences program (CFDA 47.074). The research aims to promote progress in the biological sciences by increasing scientific...
This $300,000 National Science Foundation (NSF) EAGER award to President and Fellows of Harvard College, also known as Harvard University, aims to identify the genetic factors that determine the host range of plasmid-dependent bacteriophages. Plasmids are DNA structures that can transfer genes, including those for antibiotic resistance, between bacteria through horizontal gene transfer. This project leverages a unique collection of novel plasmid-dependent phages to investigate how small...
This Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) supports research at Lehigh University to explore how biomaterials can be used to precisely control the delivery and function of CRISPR gene editing tools. The central goal is to understand how the physical and chemical properties of nanoparticles and 3D hydrogels impact CRISPR uptake, activity, and targeting to enhance its safety and efficacy. The $117,074 award,...
This five-year $385,645 Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) will fund research investigating RNA-guided nucleases encoded by transposons across the three domains of life. The grantee, Columbia University, will examine an ancestral family of transposon-encoded enzymes that use guide RNAs to target and cut matching DNA sequences. These enzymes are directly related to CRISPR-Cas9 and CRISPR-Cas12 genome editing tools. The project aims to...
The National Science Foundation (NSF) awarded a $800,000 Project Grant under its Biological Sciences program (CFDA 47.074) to The Regents of the University of California, doing business as University of California, Berkeley. The grant funding will support collaborative research to discover and characterize compact CRISPR gene editing systems that can be encoded in plant viruses. This will enable more efficient and widespread deployment of genome editing capabilities across a variety of crop...