Project Grant 2422796
Award Date
4/15/25
Completion Date
3/31/28
Dollars Obligated
$519K
Federal Grant Program
47.041
Assistance Type
Project Grant
Place of Performance
Boston, MA 02215, USA
Similar Awards
This National Science Foundation (NSF) Project Grant under the CFDA program "Biological Sciences" (47.074) is awarded to Trustees of Boston University to develop and optimize optogenetic tools for selecting bacterial cells based on dynamic, time-varying traits. The $796,158 award, effective August 1, 2023 through July 31, 2026, supports the researchers in creating light-inducible genetic constructs that trigger antibiotic resistance, enabling the isolation of bacteria exhibiting...
The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $647,750 Project Grant to Princeton University under the Biological Sciences grant program (CFDA 47.074) to develop a closed-loop control system for regulating microbial communities. The project aims to integrate optogenetic controls and metabolite biosensing to dynamically modulate the composition and productivity of synthetic microbial communities for the production of valuable chemicals. The...
The National Science Foundation (NSF) awarded a $626,831 Project Grant under its Biological Sciences program (CFDA 47.074) to the University of Wisconsin-Milwaukee (UWM) to conduct collaborative research on the molecular mechanisms behind how certain bacteria use light-sensing proteins called phytochromes to regulate essential developmental processes. The project aims to use advanced structural biology techniques like cryo-electron microscopy and time-resolved X-ray crystallography to study...
The National Science Foundation (NSF) awarded a $740,797 Project Grant under the Biological Sciences federal grant program (CFDA 47.074) to the Regents of the University of California, San Francisco (UCSF) to develop and test new methodologies for the rational design of minimalistic light-switchable single-domain proteins. The goal is to engineer these proteins to bind specifically to target proteins in only one photoswitchable chromophore state, allowing for precise spatial and temporal control...
This Project Grant award from the National Science Foundation (NSF) under the Biological Sciences program (CFDA 47.074) provides $369,297 to San Francisco State University to develop a synthetic transhydrogenation module to enhance the production of valuable chemical compounds using engineered organisms. The key objectives are to: 1) understand and modify enzymes controlling cellular metabolism to enable more efficient production of high-value chemicals, 2) train undergraduate students in...
The Trustees of Boston University will use a $638,578 project grant from the National Science Foundation to develop deep learning models for microbial image analysis and time-series predictions under the Biological Sciences program. The three-year award, issued on January 1, 2022 and set to conclude December 31, 2024, will support efforts to promote progress in the biological sciences through increased understanding of major problems confronting the nation. Specifically, the university will...
This National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) Project Grant award of $373,168 supports collaborative research between the University of Wisconsin-Milwaukee and Northeastern Illinois University to understand the molecular mechanisms behind how myxobacteria use phytochromes to sense light and convert that signal into developmental changes, such as fruiting body formation. The research will utilize cutting-edge techniques including time-resolved X-ray...
The National Science Foundation (NSF) awarded a $949,877 Project Grant to Rutgers, The State University through the Biological Sciences (CFDA 47.074) program. The grant funds a collaborative research project to develop closed-loop control systems that integrate optogenetics and metabolite biosensing to modulate the composition and productivity of synthetic microbial communities. The project aims to advance basic research in this area and generate strategies for improved production of...
This National Science Foundation (NSF) Project Grant, under the Mathematical and Physical Sciences (CFDA 47.049) program, supports computational research and education focused on understanding the interaction of light with ordered assemblies of carbon-based organic molecules. The goal is to advance the design of more efficient and cost-effective solar energy conversion materials. Through first-principles electronic structure theory modeling, the researchers at Boston University will...
This federal Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) provides $200,348 to Trustees of Tufts College (Tufts University) to develop modular biological robots with variable morphology. The key products and services to be delivered include: The project will create functional biobot modules controlled by different colors of light, enabling biobots to split apart or join together on command. Predictive numerical simulations and advanced...