Project Grant 2422619
- The National Science Foundation (NSF) awarded a $225,000 Project Grant under the Biological Sciences (CFDA 47.074) program to Carnegie Mellon University and Purdue University. The grant, awarded on August 15, 2025, will support the development of a cyberinfrastructure that enables the analysis of cryo-electron tomography (cryo-ET) data. The project aims to build an open-access, annotated database of cryo-ET images and a robust toolbox of computational methods for their analysis. The resulting...
- Carnegie Mellon University was awarded a $448,000 project grant from the National Science Foundation Division of Information and Intelligent Systems under the Computer and Information Science and Engineering federal grant program (CFDA 47.070). The three-year award will support the development of computational methods and software to enable the systematic de novo identification of macromolecular complexes in cryo-electron tomography images. Specifically, the university will create a...
- This Project Grant award from the National Science Foundation's (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program provides $980,943 to Purdue University from August 1, 2025 to July 31, 2029. The project aims to develop new artificial intelligence (AI) tools that can automatically interpret cryogenic electron microscopy (cryo-EM) data into accurate 3D molecular structures and validate those structures for errors. The key objectives are: (1) developing deep learning methods to...
- This Project Grant award from the National Science Foundation's (NSF) Computer and Information Science and Engineering (CISE) program, CFDA 47.070, provides $310,000 to the University of Southern California (USC) to develop an innovative training program targeting the materials science research community that relies on advanced microscopes. The key products and services to be delivered through this 3-year project, titled "CITEAM", include training on microscope data processing, the use...
- This Project Grant award in the amount of $380,000 was provided by the National Science Foundation (NSF) under the Computer and Information Science and Engineering (CISE) Federal Grant Program (CFDA 47.070) to the University of North Carolina at Chapel Hill (UNC-CH). The purpose of this grant is to develop an innovative training program targeting the materials science research community that relies on advanced microscopes, such as transmission electron microscopes (TEM), for their research....
- Purdue University was awarded a $399,459 project grant from the National Science Foundation's (NSF) Computer and Information Science and Engineering program to develop computational methods for the systematic identification of unknown biomolecular structures from cryo-electron tomography images. Over a three-year period ending in September 2025, the university will create an automated computational pipeline integrating novel techniques for fast subtomogram alignment, shape searching against...
- This Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) provides $1,150,000 to the Donald Danforth Plant Science Center to develop and share high-resolution in situ 3D cryogenic workflows to transform plant cell biology research. The goal is to overcome challenges in cryogenically preserving plant tissue samples to enable unprecedented observations of plant cell and tissue ultrastructure using volume electron microscopy and cryo-electron...
- This $599,999 project grant awarded by the National Science Foundation's Geosciences Program (CFDA 47.050) aims to develop an affordable and scalable cyber-infrastructure for reconstructing the 3D morphology of foraminifera shells from 2D microscope images. The infrastructure will leverage robotic imaging devices and artificial intelligence to create an accessible platform for scientists, students, and citizen scientists to study these tiny marine organisms, which have a rich fossil record....
- This $199,998 Project Grant from the National Science Foundation's Division of Biological Infrastructure, under the Biological Sciences program (CFDA 47.074), will fund Montana Technological University to acquire, maintain, and operate an Hitachi HT7800 electron microscope. The microscope will advance interdisciplinary research, education, and outreach in biology, chemistry, geochemistry, mechanical engineering, environmental engineering, and geology. It will strengthen PhD programs in materials...
- This Project Grant awarded by the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) federal grant program provides $250,000 to the University of California, Davis to develop fast and robust algorithms for 3D molecular structure reconstruction from cryo-electron microscopy (cryo-EM) data. The project aims to overcome the computational barriers limiting the widespread adoption of cryo-EM by creating new algorithms for image alignment and molecular...
This Project Grant award from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) provides $225,000.00 to Carnegie Mellon University and Purdue University to develop a cyberinfrastructure to support the analysis of cryo-electron tomography (cryo-ET) data. The project will build an open-access, annotated database of cryo-ET images, both simulated and experimentally obtained, alongside a toolbox of computational methods for their analysis. This infrastructure will lower the entry barrier for new researchers, promote collaboration, and accelerate scientific discoveries across the life sciences. The award also includes an educational outreach component to train Ph.D., graduate, and undergraduate students, as well as workshops for the broader research community. The resulting tools and resources are expected to support innovations in medical imaging, materials science, and workforce development in data-driven scientific fields.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $225.0k | 7/25/25 |