Project Grant 2422218
- The National Science Foundation (NSF) awarded a $919,999 Project Grant under the Biological Sciences program (CFDA 47.074) to the Regents of the University of California at Riverside. This 3-year grant, beginning September 1, 2023, supports research to investigate the evolution and functional role of small regulatory RNAs (sRNAs) in diverse bacterial lineages, particularly those living symbiotically within pest insect hosts. The project aims to determine how sRNA sequence divergence and...
- This National Science Foundation (NSF) Project Grant under the CFDA program "Biological Sciences" (47.074) is awarded to Trustees of Boston University to develop and optimize optogenetic tools for selecting bacterial cells based on dynamic, time-varying traits. The $796,158 award, effective August 1, 2023 through July 31, 2026, supports the researchers in creating light-inducible genetic constructs that trigger antibiotic resistance, enabling the isolation of bacteria exhibiting...
- This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Project Grant award, totaling $1,117,922.00, supports research to determine the mechanisms of bacterial tyrosine kinase activation and regulation. The Research Foundation of the City University of New York will utilize computational and experimental methods, including biochemical assays, NMR spectroscopy, and mass spectrometry, to investigate the activation of bacterial BY-kinases in both Gram-positive and Gram-negative...
- This $325,937 Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports collaborative research at Michigan State University (MSU) to interrogate the interconnection of structural and metabolic dynamics of evolutionarily distinct bacterial microcompartments. The project aims to study the impact of geometry and permeability of microcompartments in two distantly related bacteria under varying realistic environments, with the goal of gaining...
- This National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) Project Grant award of $900,000.00 to Colorado State University (CSU) aims to develop a novel microbiome modeling platform. The platform will integrate omics data, thermodynamics principles, metabolic models, and artificial intelligence to unravel the metabolism, interactions, and evolution of microbiomes. This research will be applied to address specific questions regarding the microbiome of a "rewired...
- This National Science Foundation (NSF) Project Grant under the Biological Sciences program (CFDA 47.074) was awarded to Bigelow Laboratory for Ocean Sciences for $396,577 to conduct research on the evolutionary patterns, systematics, and biogeographic distribution of two abundant but understudied groups of bacteria known as Patescibacteria and Chloroflexota. The research aims to improve fundamental knowledge about these cryptic microbes that play important roles in marine sediment ecosystems and...
- This Project Grant from the National Science Foundation's Division of Molecular and Cellular Biosciences provides $753,010 to California State University, Dominguez Hills Foundation from July 2021 through June 2025. The grant supports research titled "NSF RUI: CHARACTERIZING ADAPTATION TO HETEROGENOUS AND STRESSFUL ENVIRONMENTS" under the Biological Sciences program (CFDA 47.074). The Biological Sciences program aims to promote progress in the biological sciences and strengthen the...
- This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) project grant awarded to Baylor College of Medicine seeks to uncover the specific genes that confer antibiotic resistance in E. coli through a novel approach inspired by statistical physics. The $1,534,925 award spanning Aug 2024 to Jul 2027 will grow E. coli cultures and analyze the mutational ensemble using thermodynamic principles to predict the genes underlying antibiotic resistance. This technique aims to bridge...
- The National Science Foundation (NSF) Biological Sciences Federal Grant Program (CFDA 47.074) awarded a $819,654 Project Grant to the University of North Texas on February 1, 2025. The grant supports research to advance the understanding of methanotrophic bacteria metabolism and physiology. The project aims to leverage recent genetic tools and CRISPR interference techniques to further define the role of CO2 and the Ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) in the metabolism and...
- The National Science Foundation (NSF) awarded a $527,059 Project Grant through its Integrative Activities program (CFDA 47.083) to The University Corporation, a non-profit organization affiliated with California State University, Northridge (CSUN). This grant will fund the acquisition of a high-performance computer cluster for computational biology research and education at CSUN. The cluster will enable the analysis of larger datasets and more complex simulations, advancing research in areas...
This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) project grant awarded to The University Corporation at California State University, Northridge (CSUN) totals $997,047 over the period from July 15, 2024 to June 30, 2028. The project aims to uncover the genome-wide role of the AcrR regulator in controlling metabolic pathways and physiological functions in Gram-negative bacteria. Specifically, the research will identify the network of metabolic genes directly regulated by AcrR and the array of metabolic ligands that control its function. This work is expected to transform the understanding of how bacteria maintain homeostasis and adapt to toxic molecules, metabolic stress, and environmental changes. The project does not include any sub-awards.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $997.0k | 7/23/24 |