This Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) provides $284,857 to The Washington University in St. Louis to support research on the coordination and force transmission of beating cilia. The 3-year project, running from March 2025 to February 2028, will study how coordination of cilia movement is maintained in the single-celled organism Tetrahymena. Specifically, the research will measure deformations of basal bodies, quantify...
The National Science Foundation awarded a $249,998 Project Grant to the University of North Carolina at Greensboro under the Mathematical and Physical Sciences federal grant program (CFDA 47.049) to support research investigating the emergence of collective behavior in motile cilia. Dr. Ahmed will synthesize the first chemically powered, individually autonomous artificial cilia to produce a model system for studying biological cilia. This will allow customized control over cilia organization...
This National Science Foundation (NSF) Project Grant, awarded under the Biological Sciences program (CFDA 47.074), aims to enhance the understanding of motile cilia and flagella - cellular structures responsible for locomotion in many single-celled eukaryotes and the movement of fluids in multicellular organisms. The $291,710 award to President and Fellows of Harvard College will support a comprehensive, integrated research approach to study the axoneme, the highly conserved functional unit...
This Project Grant award from the National Science Foundation (CFDA 47.041 - Engineering) in the amount of $1,212,392 will support research at Cornell University to develop artificial robotic cilia metasurfaces capable of sensing environmental changes and autonomously manipulating fluid flows. The key objectives are to: (1) design, fabricate, and test low-power optical, chemical, and thermal sensors to monitor the environment; (2) develop programmable low-power control circuits to actuate the...
This $276,326 project grant, awarded by the National Science Foundation (NSF) under the Engineering program (CFDA 47.041), aims to advance the scientific understanding of the fluid flow dynamics of eukaryotic flagella and cilia. The research team at the Research Foundation for the State University of New York (RF SUNY) will use state-of-the-art microscopy and machine learning techniques to investigate the 3D flow fields induced by the beating of flagella in wild-type and mutant green algae....
This Project Grant award, provided by the National Science Foundation (NSF) Engineering program (CFDA 47.041), will support a collaborative research study on the collective dynamics of multiple flagella in a bacterial bundle. The research aims to understand how the multiple flagella of peritrichous bacteria, such as E. coli, synchronize and rotate collectively to enable bacterial swimming. The $195,656 award, with a performance period from July 1, 2024 to June 30, 2027, will integrate...
The Pennsylvania State University received a three-year, $318,782 Project Grant award from the National Science Foundation to conduct research titled "COLLABORATIVE RESEARCH: SCALING OF CILIARY FLOWS AT INTERMEDIATE REYNOLDS NUMBER." The goal of the research is to improve understanding of ciliary flows, or fluid flows generated by the beating of microscopic hairs called cilia, at intermediate Reynolds numbers. The NSF Directorate for Engineering seeks to foster innovation and...
This National Science Foundation (NSF) Project Grant under the Engineering program (CFDA 47.041) supports a collaborative research study on the collective dynamics of multiple flagella in a bacterial bundle. The $354,066 award to the Regents of the University of Minnesota aims to reveal how the multiple flagella of peritrichous bacteria like E. coli synchronize to form a functioning bundle, which is critical for their swimming and chemotaxis. The project will integrate macroscopic model...
This National Science Foundation (NSF) project grant under the Engineering program (CFDA 47.041) provides $616,151 to support fundamental research on the mechanisms by which mechanical forces regulate cell mechanics and multicellular organization. The award, effective from September 1, 2024 through August 31, 2027, will fund investigations into how intercellular adhesion proteins and cell mechanics influence the assembly and behavior of complex tissues. This interdisciplinary research...
The Regents of the University of Minnesota was awarded a three-year, $382,255 project grant from the National Science Foundation Division of Civil, Mechanical, and Manufacturing Innovation under the Engineering (CFDA 47.041) federal grant program. The grant will support collaborative research between the University of Minnesota and other institutions to experimentally study and numerically model the fluid flow dynamics of beating eukaryotic flagella. Researchers will use optical microscopy...