The National Science Foundation awarded an $827,312 project grant to the University of Nebraska under the Biological Sciences program (CFDA 47.074) to support research titled "Physiology of Hypoxia Adaptation in the World's Highest-Dwelling Mammal" from August 1, 2021 through July 31, 2024. The University will conduct basic research to increase scientific knowledge and understanding of how mammals physiologically adapt to life at high altitudes. Subawards were provided to Universidad...
This Project Grant award of $643,799.00 from the National Science Foundation's Biological Sciences (CFDA 47.074) Federal Grant Program will support research to investigate whether low oxygen levels at high elevations prevent animal species from migrating upslope in response to climate change. The research, conducted by the University of Colorado-Denver, will use dragonflies as a model organism to: (1) test how flight performance is affected when dragonflies are transplanted to different...
The National Science Foundation (NSF) awarded a $1,363,205 Project Grant under its Biological Sciences program (CFDA 47.074) to the University of California, San Diego (UCSD) to conduct collaborative research on oxygen transport mechanisms in elite diving mammals. The project aims to investigate differences in how oxygen is delivered to skeletal muscles in pinnipeds (e.g., sea lions) versus cetaceans (e.g., dolphins) during long-duration dives. The research team will evaluate in vivo oxygen...
The National Science Foundation awarded $414,000 under the Biological Sciences federal grant program (CFDA 47.074) to support an NSF Postdoctoral Fellowship in Biology from August 1, 2022 to July 31, 2025. The fellowship funding will support integrative research investigating the intersection of genomes, environments, and phenotypes in elevational migrant bird species across the Andes and Himalayas. The fellow will generate valuable museum specimens including frozen tissues and genomic,...
This National Science Foundation (NSF) project grant, awarded under the Biological Sciences program (CFDA 47.074), will provide $1,225,175.00 to support a 3-year study at Wayne State University on the adaptation of the cytochrome c oxidase enzyme in response to hypoxic (low oxygen) conditions in systemic vascular cells. The key objectives are to: 1) characterize the dynamic regulation of cytochrome c oxidase subunit isoform composition in systemic pericytes and vascular cells under chronic...
The National Science Foundation Division of Emerging Frontiers awarded a $546,576 project grant to the University of California Santa Cruz under the Biological Sciences federal grant program (CFDA 47.074) to support collaborative research on physiological adaptation and speciation in extreme environments from January 1, 2023 to December 31, 2023. The award will fund integrated analyses of how selection shapes genomic divergence between fish populations living in hydrogen sulfide-rich springs...
This $999,996 Project Grant award, provided by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074), supports fundamental research aimed at generating "designer mitochondria" for biotechnology, healthcare, and basic research applications. The key objectives are to identify the factors required for human mitochondrial DNA (mtDNA) replication and characterize the mechanisms underlying the species-specificity of this process. This work represents a critical step...
The National Science Foundation awarded a $243,897 project grant under the Integrative Activities program (CFDA 47.083) to The University of New Mexico from August 15, 2022 to July 31, 2025. The grant funds research to investigate the biological function of a toxin-like molecule discovered in the recently sequenced genome of the African lungfish. Known as Protop-CTXA, this molecule is hypothesized to play an important role in lungfish estivation by breaking down skin integrity to form a...
This three-year $632,382 project grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) will fund research to understand how behavioral adaptations in foraging effort by wandering albatrosses (Diomedea exulans) and black-browed albatrosses (Thalassarche melanophris) may mitigate population declines due to climate change. The awardee, the Regents of the University of Colorado, will assess linkages between climate change, body condition, foraging effort,...
This $332,924 National Science Foundation project grant under the Biological Sciences program (CFDA 47.074) funds research at the University of Nebraska from August 2022 to July 2025 investigating convergent evolution of mitochondrial cytochrome c maturation systems in plant and algal species. The research will use molecular biology, genetics, plant growth assays, and computational analysis to study numerous pathway switches and assess the mechanisms and evolutionary importance when there is...