This Project Grant award of $900,000.00 from the National Science Foundation's (NSF) Division of Chemistry, under the Mathematical and Physical Sciences Federal Grant Program (CFDA 47.049), supports research by Professors Houk and Tang of the University of California, Los Angeles (UCLA) to study the development of a new class of enzymes called "pericyclases." The researchers aim to characterize the mechanisms by which these enzymes catalyze natural product biosynthetic reactions, understand how nature evolved common protein folds into dedicated pericyclases, and establish whether electrocyclases exist in nature. The project will expand the fundamental understanding of enzyme catalysis and broaden the scope of catalysis to pericyclases. No sub-awards are planned for this award, which has an award date of September 1, 2024, and an ultimate completion date of August 31, 2027.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $900.0k | 8/19/24 |