North Carolina State University will synthesize functional biomolecules from tunable N-aryl peptide precursors under a $976,087 project grant from the National Science Foundation Division of Chemistry. The grant was awarded on May 1, 2021 for a five-year period concluding on April 30, 2026. The grant supports work under the NSF's Mathematical and Physical Sciences program (CFDA 47.049), which aims to promote progress in these scientific fields and strengthen the national scientific enterprise....
This $447,000 Project Grant from the National Science Foundation's Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), will support research at Haverford College from December 2022 through February 2026. The research team, led by Dr. Louise Charkoudian, will investigate type II polyketide biosynthetic enzyme assemblies across bacterial species to leverage their capabilities for sustainable chemical production. Undergraduate students will gain research...
This Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) provides $600,000 in funding to the University of Delaware to develop new methods for the synthesis of cyclic molecules containing oxygen and nitrogen atoms. The primary focus is on establishing enantioselective copper-catalyzed additions of alkynes to cyclic oxocarbenium and iminium ion intermediates to efficiently produce oxygen and nitrogen heterocycles with...
This $640,000 Project Grant award from the National Science Foundation's (NSF) Division of Chemistry, under the Mathematical and Physical Sciences (CFDA 47.049) Federal Grant Program, supports a collaborative research effort between Professors Wooley and Darensbourg of Texas A&M University. The objective is to develop sustainable synthetic methodologies that harness the chemical diversity of natural products to produce next-generation macromolecular materials. The proposed work aims to...
This Project Grant from the National Science Foundation's Division of Human Resource Development provides $299,835 to Winston-Salem State University under the STEM Education program (CFDA 47.076) from August 2022 through July 2025. The university will use this funding to support faculty and undergraduate research investigating perfluoroalkyl substances (PFAS), a class of commonly used environmental toxins. Specifically, the researchers will conduct a comprehensive analysis using various...
Florida State University will receive $450,000 from the National Science Foundation under the Mathematical and Physical Sciences program (CFDA 47.049) to support research on more efficient synthesis of complex biologically active natural products from August 1, 2022 to July 31, 2025. Principal Investigator Joel M. Smith and his team will develop novel strategies for constructing challenging molecular architectures found in nature, such as piperidine alkaloids. This work will provide new insights...
This $650,000 Project Grant awarded by the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) funds an industrial-academic collaboration between Princeton University and the Merck Catalysis Laboratory. The goal is to develop new sustainable catalytic methods for the large-scale synthesis of pharmaceutical drugs using earth-abundant metals like iron, cobalt, and nickel instead of rare precious metals. The research aims to identify viable catalytic...
This $575,000 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) supports a collaborative research project led by Professors Keary Engle of the Scripps Research Institute and Peng Liu of the University of Pittsburgh. The project focuses on developing new chemical reactions using earth-abundant nickel catalysts to efficiently synthesize valuable compounds, including medicinally relevant molecules, agrochemicals, and functional...
This $575,000 Project Grant award from the National Science Foundation's Mathematical and Physical Sciences (CFDA 47.049) program to the University of California, Berkeley will support Professor Thomas Maimone's research on developing new synthetic strategies for constructing complex, nitrogen-containing molecules. The work aims to identify transformations that can efficiently produce unique target molecules with potential applications in pharmaceuticals, agrochemicals, and materials. The...
This $391,841 federal Project Grant award, funded by the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) program, supports research conducted by Professor Gregory O'Neil of Western Washington University (WWU) to develop new stereoselective synthesis methods using allyl organosamarium intermediates. The goal is to create new reactions that can precisely control the three-dimensional arrangement of atoms in carbon-based molecules, which is essential for...