Under a $595,000 Project Grant from the National Science Foundation's Mathematical and Physical Sciences (CFDA 47.049) program, Professor Thomas Lectka of Johns Hopkins University will pursue two complementary strategies to selectively modify specific carbon-hydrogen or carbon-carbon bonds within complex molecular structures. The first approach will utilize hydrogen bonding to direct site-selective functionalization reactions, while the second will leverage metal ion binding to deactivate undesirable reaction sites. This research aims to advance the field of site-selective organic synthesis, which has broad applications in chemistry, biology, and medicine. The award will also support the professional development of graduate students and provide research experiences for undergraduates. No federal sub-awards are planned under this grant, which runs from September 2024 through August 2027.
Generated 12/31/24, 12:26 PM