This $575,000 federal Project Grant, awarded by the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) program, supports the University of North Carolina at Chapel Hill in developing new sustainable nickel-catalyzed coupling methods for the stereoselective synthesis of complex organic molecules. The 3-year project, led by Professor Simon Meek, focuses on creating efficient, site- and stereo-controlled multicomponent reactions using simple carbonyl-type electrophiles and readily available unsaturated hydrocarbons. These transformations enable the formation of two new bonds and up to three new stereocenters, unlocking the production of important functionalized acyclic and cyclic molecular scaffolds. Additionally, the project includes educational components, such as involving undergraduate students and integrating comprehensive instructional elements across different course levels, to enrich STEM education. No sub-awards are planned for this award.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $575.0k | 6/26/24 |