This Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) will support research to identify the specific roles that zinc plays in the sensation of taste. The $773,887 award, effective April 1, 2025 through March 31, 2030, will fund the University of Nebraska's efforts to: Use gene expression studies, CRISPR knockout screens, and single-cell analysis in mouse taste organoids to identify key zinc transporters and zinc-regulated genes involved...
The National Science Foundation (NSF) awarded a $444,362 Project Grant under the Biological Sciences program (CFDA 47.074) to the University of Vermont & State Agricultural College, to be completed by April 30, 2027. This research project aims to investigate amino acid taste coding mechanisms and modulation in the fruit fly, Drosophila melanogaster. The primary objectives are to: 1) identify physiological factors that modulate amino acid taste response, 2) uncover the repertoire of cells and...
This $970,670 Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports research by the University of Cincinnati to examine how the sensory system of taste evolves in fish populations living in different aquatic environments. The researchers will analyze taste receptor genes, visualize taste bud distribution, and correlate these findings with the chemical composition of the fish's habitat. This comprehensive study aims to provide insights...
The National Science Foundation Division of Molecular and Cellular Biosciences awarded Virginia Polytechnic Institute & State University a $805,420 Project Grant under the Biological Sciences federal grant program (CFDA 47.074) for the period of August 1, 2021 through July 31, 2025. The grant funds collaborative research on chemotactic signaling in Sinorhizobium meliloti symbiotic plant host interaction. The Biological Sciences program aims to promote advancement in the biological sciences...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) provides $1,170,404.00 over approximately 5 years beginning Jun 15, 2024 to characterize unknown small molecules in humans using a combination of organic synthesis, mass spectrometry, and public data mining. The key products and services to be delivered include: 1) Synthesizing and detecting neurotransmitter derivatives and...
This Project Grant award of $260,138 from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) supports collaborative research to understand the structure-property relationships of bioinspired lipid membranes. The research team at Virginia Polytechnic Institute & State University (Virginia Tech) will use experimental methods like neutron spectroscopy and molecular dynamics simulations to investigate how variations in lipid and sterol compositions...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training Program (CFDA 93.859) provides $1,188,963 to Virginia Polytechnic Institute & State University (Virginia Tech) to support research on resolving the cellular functions of arginine methylation by the enzyme PRMT5. The project aims to explore how PRMT5 methylation of substrate proteins affects their ability to bind to mRNA, interact with other proteins,...
This $841,009 federal Project Grant award from the National Science Foundation's (NSF) Biological Sciences program will support research at Virginia Polytechnic Institute & State University (Virginia Tech) to investigate the regulatory mechanisms of endosomal cargo transporters. The project aims to determine the molecular mechanisms governing the regulation of the endosomal cargo transporter TOM1, which plays a critical role in intracellular protein trafficking. Using a combination of...
Virginia Polytechnic Institute & State University (Virginia Tech) was awarded a $1,000,000 Project Grant from the National Science Foundation (NSF) Division of Information and Intelligent Systems. The award will support research from October 1, 2021 to September 30, 2025 under the NSF's Computer and Information Science and Engineering program (CFDA 47.070). Specifically, Virginia Tech will conduct research titled "III:MEDIUM:PHYSICS-GUIDED MACHINE LEARNING FOR PREDICTING CELL...
Virginia Polytechnic Institute and State University (Virginia Tech) was awarded a $181,968 Project Grant from the National Science Foundation's (NSF) Mathematical and Physical Sciences program to conduct collaborative research on quantitative-sequence experiments from August 1, 2023 to July 31, 2026. The grant aims to provide systematic solutions for designing, modeling, quantifying uncertainty, and applying active learning techniques to experiments involving both quantitative and sequence...