This Project Grant award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) is providing $275,000 to Dinya DNA Inc. to support the commercial development of a novel DNA synthesis technology. The key products or services being delivered include: Developing new methods to ensure higher fidelity DNA precursors, which are the building blocks for DNA synthesis Reducing synthesis costs by streamlining the DNA synthesis reactions...
This $1,250,000 Cooperative Agreement award from the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) aims to develop an innovative platform for preparing DNA samples for long-read sequencing technologies. The project, awarded to Micropure Genomics Inc., a minority-owned small business, focuses on fabricating user-friendly cartridges and instruments, improving platform performance, and validating the technology with leading...
This SBIR Phase I award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $274,932 to Femtofluidics Incorporated to develop hardware that can rapidly and inexpensively synthesize DNA-encoded libraries (DELs) for accelerating drug discovery. The project aims to build a device that can perform combinatorial chemistry on nanoliter to picoliter droplets using an electronic substrate, without any moving or mechanical parts. This...
This $305,000 Project Grant award from the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) supports the development of a microchip-based technology for advanced cell engineering. The awardee, Cellecho, Inc., aims to create a platform that leverages sound waves and electric fields to manipulate cells and deliver customizable combinations of genetic materials with high efficiency and throughput. This innovation has the...
This $1,384,726 Project Grant award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) supports the development of an open-source ecosystem for nucleic acid nanotechnology modeling. The project aims to transition the existing oxDNA software, which provides simulation models and design tools for computer-based testing and validation of nucleic acid nanostructures, into a mature open-source ecosystem. This will enable...
Micropure Genomics Inc. received a $274,199 Project Grant award from the National Science Foundation to advance methods for rapid, end-to-end sample preparation for sequencing applications. Under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084), the company will develop an automated process relying on electro-hydrodynamic trapping to isolate genomic material like DNA or RNA from cells in a flow cartridge. The process aims to significantly reduce preparation time while...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award supports the development of a novel device that can rapidly and automatically extract pathogen DNA from whole blood samples to enable faster diagnosis of sepsis. The $274,858 award to New England Hemolytics, Inc., with a project period from September 1, 2024 to February 28, 2025, will fund the testing and optimization of this technology across common sepsis-causing pathogens. The...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award for $275,000 will support the development of a plasmonic nanopore sensor device for quality control of adeno-associated viruses (AAVs) used in gene therapy. The proposed device will enable accurate characterization of AAV payload (single-stranded DNA, double-stranded DNA, or empty) at low, pre-scale-up concentrations to optimize formulations. The project aims to demonstrate the...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program award provides $274,990 to Dencoda LLC to develop a novel DNA-based kinase assay platform. The key products to be delivered are: A highly sensitive, specific, and multiplexed kinase activity assay that can be used as a research tool to discover new therapeutic targets or as a clinical diagnostic test for diseases involving kinase dysregulation, such as cancers, diabetes, and Alzheimer's disease....
The National Science Foundation awarded a $299,178 project grant to Bigelow Laboratory For Ocean Sciences for work titled "EAGER: ENCAPSULATION AND SEQUENCING OF EXTRACELLULAR DNA." The two-year grant running from April 2021 through March 2023 is funded through the NSF's Geosciences program (CFDA 47.050). Under the award, Bigelow Laboratory will conduct research to encapsulate and sequence extracellular DNA found in ocean environments. The NSF's Geosciences program supports basic...