This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $273,550 to Biocognon LLC provides funding to develop a novel yeast-based high-throughput screening platform for efficiently generating molecular recognition domains that can specifically recognize clinically important targets. The goal is to integrate breakthroughs in next-generation DNA sequencing, synthetic biology, and computational biology to create a combinatorial...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Phase I Small Business Innovation Research (SBIR) grant for $275,000 aims to develop new bacterial strains capable of efficiently producing difficult-to-express proteins through precision fermentation. The project seeks to engineer improved bacterial hosts to manufacture proteins used in detergents, personal care products, and dairy, enabling the production of these products with lower environmental...
The National Science Foundation (NSF) awarded a $274,438 SBIR Phase I grant to Script Biosciences Inc. under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program. The project, titled "CASPLUS: A Safer, More Efficient, and Targeted Method of Deploying CRISPR In Vivo," aims to develop a platform technology that significantly reduces the potential inaccuracy of current gene editing techniques. The innovation targets the desired gene, increasing the safety and efficacy...
This National Science Foundation (NSF) Project Grant, under the Biological Sciences program (CFDA 47.074), provides $683,512 to Clark University to conduct research on the genetic mechanisms underlying morphological evolution in mushrooms. The key products and services to be delivered under this 3-year award (01/01/2024 - 12/31/2026) include:
Resolving the higher-level phylogenetic relationships within the fungal genus Lentinus using genomic data from living cultures and herbarium...
This Project Grant award from the National Science Foundation (CFDA 47.084 - NSF Technology, Innovation, and Partnerships program) provides $275,000 to Ubiquitx Inc., a New York-based small business, to develop a programmable, modular therapeutic platform for the direct modification of proteins of interest (POIs) using artificial intelligence, protein engineering, and mRNA therapeutics. The goal is to expand the applications of the company's Chimeric Ligands for Induced Proximity (CLIPS)...
The National Science Foundation (NSF) awarded Pearl Bio, Inc., a biotechnology company, a $274,462 Project Grant under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084). The grant funded the development of a next-generation biomanufacturing platform to engineer new microbial organisms and cellular machinery. This platform enables the incorporation of diverse, non-native components into proteins, creating a new class of biological materials for therapeutic development,...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $308,925 to Chemia Biosciences, Inc. to develop computational methods and software tools for discovering novel natural products from fungal species.
The project aims to leverage high-throughput mass spectrometry and genome mining techniques to identify new molecular compounds with potential antibiotic and therapeutic...
This Project Grant award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $275,000 in funding to Myconaut LLC to develop a scalable biological remediation method that uses synergistic interactions between fungi and plants to degrade and remove per- and polyfluoroalkyl substances (PFAS) from contaminated environments. The project aims to expand the understanding of fungal degradation of PFAS, evaluate the...
This $275,000 SBIR Phase I Project Grant, awarded by the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program, aims to develop a generalized process to formulate and stabilize beneficial microbes for widespread adoption. The project, conducted by Seia Bio Inc., seeks to address the challenge of microbial stability when exposed to stressors such as heat, UV light, shock, and humidity. The proposed R&D will advance the understanding...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $273,910 provides funding to Bluestem Biosciences Inc. to research and develop more energy-efficient methods for the anaerobic bioproduction of valuable organic acids such as 3-hydroxypropionic acid. The goal is to create a biomanufacturing process that can reduce greenhouse gas emissions and reliance on foreign supply chains compared to current petrochemical-based methods for...