This National Science Foundation (NSF) Project Grant, awarded under the Biological Sciences program (CFDA 47.074), provides $750,000 to Stanford University to develop new technologies for studying RNA, the essential molecules that carry genetic information and play crucial roles in cell functions. The key products and services to be delivered under this 3-year award include:
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Creating non-destructive methods to directly study RNA localization and interactions within living cells, achieving single-cell resolution with improved labeling chemistries.
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Developing RNA-centric interactome mapping tools through protein engineering and directed evolution.
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Applying these technologies to study tumor-immune cell interactions and map cancer-associated RNA interactomes, in collaboration with cancer biology experts.
This multidisciplinary effort leverages Stanford's expertise in areas such as protein and RNA engineering, chemical biology, computational analysis, and cancer biology. The project aims to provide widely applicable tools, foster educational opportunities, and potentially advance cancer therapeutics, contributing to improvements in public health.
Generated 12/3/24, 7:50 AM