This National Science Foundation (NSF) Project Grant under the CFDA program "Biological Sciences" (47.074) is awarded to Trustees of Boston University to develop and optimize optogenetic tools for selecting bacterial cells based on dynamic, time-varying traits. The $796,158 award, effective August 1, 2023 through July 31, 2026, supports the researchers in creating light-inducible genetic constructs that trigger antibiotic resistance, enabling the isolation of bacteria exhibiting rapid responses or adaptive capabilities in response to environmental changes. The project aims to demonstrate this approach by studying (p)ppGpp-responsive promoters and their temporal/stochastic properties. In addition, the award includes educational outreach initiatives, such as partnering with STEM programs to host events for high school students and providing research training opportunities for undergraduates.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $796.2k | 7/17/23 |