Project Grant 2323500
- This Project Grant awarded by the National Science Foundation (NSF) under the Engineering program (CFDA 47.041) supports research to understand how human bone tissue dynamically adapts at the nanoscale level under various loading conditions. The $719,538 award to the Trustees of the University of Pennsylvania, made on May 1, 2024, will investigate the real-time rearrangement and deformation of the nanoscale components of healthy and osteoporotic bone tissue when subjected to cyclic loading....
- The National Science Foundation (NSF) Office of International Science and Engineering (CFDA 47.079) awarded a $420,000 Project Grant to Lehigh University to develop predictive computer simulation tools that can forecast bone healing progress for patients with poorly healing fractures. The 4-year project, running from October 1, 2025 to September 30, 2029, aims to create digital twin models of real bones using medical imaging data. These simulations will provide insights into individual healing...
- This federal Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) supports a research program at the University of Utah to investigate the biomechanical origins of bone fragility in aging and type-2 diabetic populations. The $328,416 award, spanning from July 15, 2025 to June 30, 2028, will explore how aging and diabetes-induced changes to the collagen network in bone impact its resistance to fracture at both physiological and fall strain rates. The...
- The National Science Foundation awarded a $280,774 Project Grant to the University of Colorado Denver under the Engineering program (CFDA 47.041) for research determining the impacts of lacunar-canalicular remodeling on bone fracture toughness. The three-year award beginning September 15, 2021 will fund collaborative research between the University of Colorado Denver's Department of Mechanical Engineering and the Regents of the University of Colorado to analyze how changes to the...
- This CAREER: PRINTED MAGNETOELECTRIC COMPOSITES AS A BIOSCAFFOLD FOR BONE TISSUE ENGINEERING federal Project Grant, awarded by the National Science Foundation (NSF) under the Mathematical and Physical Sciences program (CFDA 47.049), aims to develop a novel magnetically responsive biomaterial that can replicate the microstructures and physical stimuli of natural human bones. The $113,932 award, with a performance period from January 15, 2025 to December 31, 2029, will support research conducted...
- This National Science Foundation (NSF) Division of Materials Research Project Grant, CFDA# 47.049 Mathematical and Physical Sciences, provides $400,000 in funding to The Trustees of the University of Pennsylvania to conduct collaborative research on developing novel hybrid metal-piezoelectric biomaterials for anti-infectious implantable medical devices. The key objective is to create advanced multifunctional biomaterial platforms that can effectively prevent biofilm formation and bacterial...
- This Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) provides $270,189.00 to Virginia Polytechnic Institute & State University to investigate the role of aging and type-2 diabetes on bone fracture behavior. The research program will study how changes to the collagen network in bone, such as increased crosslinking, can reduce bone's resistance to fracture in aging and diabetic populations. The project will conduct fracture experiments,...
- This federal Project Grant award of $500,000.00, issued by the National Science Foundation's (NSF) Engineering program (CFDA 47.041), supports research at Northwestern University to develop a computational model for predicting time-dependent changes in the structure and composition of mineralized tissues. The project aims to create a robust, modular, and expandable phase field model based on structural, compositional, and thermodynamic data to better understand the interplay between...
- This Project Grant award of $612,979.00 from the National Science Foundation's Engineering program (CFDA 47.041) supports research at Cornell University to investigate the role of acetylcholine signaling in osteocyte mechanotransduction and bone remodeling. The project aims to characterize the anatomical and functional relationship between cholinergic nerves and osteocytes, examine the acute effects of acetylcholine signaling on osteocyte calcium responses to mechanical loading, and explore...
- This National Science Foundation (NSF) CAREER award under the Engineering program (CFDA 47.041) provides $624,622 over 5 years starting September 1, 2025 to support research aimed at advancing the scientific understanding of cartilage microstructure and function. The principal investigator will leverage quantitative magnetic resonance imaging (MRI) techniques to study how changes in the microscopic structure of cartilage impact its macroscopic behavior under loading conditions experienced in...
This Project Grant award from the National Science Foundation (NSF) Division of Materials Research, under the Mathematical and Physical Sciences program (CFDA 47.049), provides $322,382 to the University of Connecticut Health Center (UCHC) from September 1, 2023 through August 31, 2026. The goals of this collaborative research project are to use computer modeling and high-energy synchrotron X-ray diffraction experiments to better understand how the incorporation of cobalt (Co) and chromium (Co) ions into apatite crystals, the mineral component of bone, can affect the mechanical properties and fracture risk of bones near cobalt-chromium implants. The research aims to develop new techniques to predict how metal ions interact with and impact the strength of apatite crystals, in order to benefit the millions of people with cobalt-chromium implants. Integrated into the research is an educational plan to increase self-efficacy in science for diverse students, including providing lab access, developing inclusive courses, and serving as role models.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $322.4k | 7/27/23 |