This $515,926 Project Grant awarded by the National Science Foundation (NSF) Engineering program (CFDA 47.041) will fund research to develop an in vitro gingival (gum) tissue system to study the role of microbial communities on oral health and disease. The 5-year project, beginning June 1, 2024, will be conducted by the University of Massachusetts Lowell's Office of Research Administration-Lowell. The key objectives are: (1) developing and validating a microphysiological system to study oral...
This Project Grant from the National Science Foundation's Engineering program (CFDA 47.041) provides $249,999 to The Trustees of the University of Pennsylvania for the development of a smart dental implant system. The award will support research and educational activities from September 2022 through August 2025. Specifically, the grantee will build a strategy to prevent peri-implant disease through enhancing soft tissue immunity near dental implants. They will develop an ambulatory care platform...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) Project Grant award of $275,000 aims to validate a novel device and approach for enhancing the delivery of pharmaceuticals and cosmetics into human teeth. The key products and services to be delivered under this award include: Validating the use of electrical voltage, current, application time, pressure, and conductive additives to improve the permeability and depth of delivery for topical...
The National Science Foundation awarded a $254,360 Project Grant to Quiver Dental, Inc. under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) to develop a diagnostic device to measure dental implant stability. The one-year award running from August 1, 2022 to July 31, 2023 aims to complete proof-of-concept demonstration of a reliable and accurate device using vibrational technology to quantify the degree of motion and stability between a dental implant and surrounding...
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121) provides $675,684 to investigate the microbial ecosystem surrounding dental implants and its relationship to peri-implantitis disease. The project aims to create a functional atlas of the peri-implant sulcus microbiome from inception to disease establishment, pinpoint timelines for breakdown of host-microbiome mutualism, and...
This federal Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), aims to develop a multi-functional, antibacterial, and bioactive 3D-printed dental implant to prevent peri-implantitis. The primary objectives are to: 1) determine the processing-structure-property relationships of the 3D-printed implant material, 2) evaluate the infection resistance and osseointegration properties of...
This Project Grant award from the National Science Foundation's (NSF) Social, Behavioral, and Economic Sciences (CFDA 47.075) program will provide $298,025 to The Trustees of the University of Pennsylvania to investigate the progression of dental wear and dental senescence over a 50-year simulated chewing period. The study will employ a mechanical chewing simulator and analysis techniques to measure changes in dental function, occlusal topography, microstructure, and elemental composition of...
This National Science Foundation Project Grant of $255,757 awarded on August 15, 2022 will fund the development of an ultrasound-based point-of-care periodontal imaging device under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084). Stylosonic LLC will develop an integrated device for acoustic imaging of the entire mouth that automatically processes imaging data to assist dentists in assessing gingival health and periodontitis. Key objectives include miniaturizing imaging...
This Project Grant from the National Science Foundation supports the development of superparamagnetic, antimicrobial nanocomposites and a magnetic toothbrush for synergistic dental care. Awarded $276,000 on June 1, 2022 under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084), the funding will support MNT Smartsolutions LLC through May 31, 2023. The company will develop a biofunctionalized magnetic nanoparticle ferropaste that can efficiently remove oral bacterial biofilms...
This $656,315 Project Grant was awarded on September 1, 2024 by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research Federal Grant Program (CFDA 93.121). The overarching goal is to mechanistically study the effect of biomaterial cyclic strain on the pathogenesis of oral microbes, including the fungal strain Candida albicans and denture-related microbiota. The research aims to understand how chewing actions may fuel the progression of...