The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $426,036 Project Grant under the Biological Sciences program (CFDA 47.074) to the Georgia TECH Research Corp, also known as the Office of Sponsored Programs, a non-profit research organization and state institution of higher education associated with the Georgia Institute of Technology. The grant aims to identify and characterize oligonucleotide-based ligands as alternatives to antibodies for protein targets called kinases. The research leverages advantages offered by oligonucleotides to broaden their practical use as biological tools across the STEM community. The project combines macromolecular synthetic design with biological activity assessment to uncover fundamental structure-binding relationships between oligonucleotide ligands and their kinase targets. This award reflects NSF's mission to promote the progress of the biological sciences and enhance understanding of major problems confronting the nation.
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