Project Grant 2318053
- The National Science Foundation (NSF) Division of Mathematical Sciences awarded a $200,000 Project Grant to the University of California, Davis (UC Davis) under the Mathematical and Physical Sciences program (CFDA 47.049). The 3-year grant, effective August 15, 2023, will fund research into the topology and infection dynamics of bacteriophage viruses. The project aims to provide a thorough characterization of DNA organization inside phage capsids and its delivery during infection, bridging...
- The Regents of the University of Minnesota, through the Office of Sponsored Projects Administration, has received a $200,000 Project Grant award from the National Science Foundation's (NSF) Division of Mathematical Sciences under the Mathematical and Physical Sciences program (CFDA 47.049). The award, effective August 15, 2023 through July 31, 2026, will support collaborative research to characterize the topology and infection dynamics of bacteriophage viruses. Key focus areas include...
- The National Science Foundation awarded a $501,269 Project Grant to Stanford University under the Mathematical and Physical Sciences program (CFDA 47.049). The grant will fund theoretical and computational modeling of supercoiling, topology, and active fluctuations in chromosomal organization and dynamics from September 2021 through August 2024. As part of the Mathematical and Physical Sciences program's goal of strengthening the Nation's scientific enterprise through increased understanding...
- The National Science Foundation (NSF) awarded a $150,000 Project Grant under the Mathematical and Physical Sciences (CFDA 47.049) federal grant program to the Georgia Tech Research Corporation. The grant, awarded on September 15, 2025, will support a research project investigating important problems in quantum topology and its connections with classical topology and hyperbolic geometry. The project aims to advance the understanding of three- and four-dimensional topology and knot theory, which...
- The National Science Foundation (NSF) awarded a $230,000 Project Grant under the Mathematical and Physical Sciences program (CFDA 47.049) to the University of North Carolina at Chapel Hill for the period of August 1, 2023 to July 31, 2026. The research project will investigate and validate a new class of Cosserat rod models to describe the stretch-limiting behavior of biological fibers like DNA and RNA. Key expected deliverables include determining the fundamental properties of these models from...
- The National Science Foundation Division of Mathematical Sciences awarded a $399,998 Project Grant to the University of South Florida to support collaborative research modeling R-loop formation and topology using braids and graphs coupled with single-molecule footprinting from August 1, 2021 to July 31, 2024. This award will fund research under the Mathematical and Physical Sciences program (CFDA 47.049), which aims to promote progress in the mathematical and physical sciences and strengthen the...
- The National Science Foundation (NSF) awarded a $149,826 Project Grant under the Mathematical and Physical Sciences Federal Grant Program (CFDA 47.049) to Trustees of Boston College for the project "FLOER HOMOLOGY IN LOW-DIMENSIONAL TOPOLOGY." This 2-year project, running from August 1, 2025 to July 31, 2027, focuses on an area of mathematics called low-dimensional topology, which studies shapes and spaces in three and four dimensions. The research aims to unify various tools from...
- The National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences awarded a $189,811 project grant to The College of Wooster under the Mathematical and Physical Sciences program (CFDA 47.049). The goal of this 2-year project is to develop an optimal combination phage cocktail and antibiotic therapy to treat antimicrobial resistant infections. The research will leverage mathematical models to identify characteristics of bacteriophages that show promise as therapeutic...
- The National Science Foundation (NSF) awarded a $219,165 Project Grant under the Mathematical and Physical Sciences Federal Grant Program (CFDA 47.049) to the University of South Alabama. The grant, titled "LEAPS-MPS: Categorification in Algebra and Topology," aims to use categorification techniques to study knot theory, which has applications in biology, medicine, chemistry, and physics. The research is expected to create new tools to address challenging open problems in knot theory...
- This $232,771 Project Grant, awarded on September 15, 2025, was provided by the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) program. The grant aims to develop computational mathematical tools to better understand protein structures and interactions, even across a wide range of mutations. This interdisciplinary research combines mathematical modeling, machine learning, and biology to analyze the complex shapes of proteins, with the goal of enabling...
The National Science Foundation (NSF) Division of Mathematical Sciences awarded a $100,000 Project Grant to the Florida Institute of Technology Inc. (doing business as Florida TECH), a private university and non-profit organization located in Melbourne, Florida. This award is funded through the NSF's Mathematical and Physical Sciences program (CFDA 47.049), which aims to promote the progress of mathematical and physical sciences and strengthen the nation's scientific enterprise. The primary focus of the project is to provide a thorough characterization of the organization and topological properties of DNA inside bacteriophage (phage) capsids, as well as the mechanisms of genome delivery during phage infection. The investigators will combine experiments and mathematical modeling to study the biophysical properties of DNA in spatial confinement, including the formation of DNA knots and their dependence on environmental ions. Additionally, the researchers will develop models to study genome release from phages at the time of infection, incorporating methods from the study of polyelectrolyte gels and protein binding. The project will train two graduate students and one postdoctoral fellow, advancing scientific knowledge and fostering the development of future researchers in this field.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $100.0k | 7/31/23 |