North Carolina State University will synthesize functional biomolecules from tunable N-aryl peptide precursors under a $976,087 project grant from the National Science Foundation Division of Chemistry. The grant was awarded on May 1, 2021 for a five-year period concluding on April 30, 2026.
The grant supports work under the NSF's Mathematical and Physical Sciences program (CFDA 47.049), which aims to promote progress in these scientific fields and strengthen the national scientific...
The National Science Foundation (NSF) awarded a $250,000 Project Grant under the Mathematical and Physical Sciences (CFDA 47.049) program to the University of North Carolina at Greensboro (UNC-G). The project, titled "LEAPS-MPS: Engineering and Evolution of Copper-Dependent Enzymes for Targeted Peptide Cyclization," will explore new enzyme catalysts to improve the stability and bioactivity of peptides, which are important molecules in agriculture, research, and medicine. The project...
The University of North Carolina at Chapel Hill will receive $495,000 from the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049) to support research into designing artificial enzymes from June 2022 to May 2025. Dr. Albert Bowers and his team will develop a generalizable strategy for separating substrate binding and catalysis functions into distinct domains for peptide-based enzymes. They will use computational protein design with Rosetta to create...
The University of North Carolina at Chapel Hill received a $300,081 Project Grant award from the National Science Foundation Division of Chemistry on August 15, 2021 to support research titled "Collaborative Research: Probing Coordination Specificity of Metalloprotein Domains with Peptide-Polymer Amphiphile Self Assembly." The award has a completion date of July 31, 2024.
The research is being conducted under the Mathematical and Physical Sciences program (CFDA #47.049) to advance...
The National Science Foundation Division of Chemistry awarded a $480,000 Project Grant to the University of North Carolina at Chapel Hill from July 1, 2021 to June 30, 2024. The grant supports the "COOPERATIVITY DRIVEN COMMUNICATION THROUGH NONCOVALENT NETWORKS IN BIOMIMETIC SYSTEMS" project under the Mathematical and Physical Sciences program (CFDA 47.049).
The University of North Carolina at Chapel Hill will conduct research exploring cooperativity and noncovalent interactions in...
The University of North Carolina at Chapel Hill (UNC-CH), through its Office of Sponsored Research, received a $529,988 Project Grant from the National Science Foundation's (NSF) Mathematical and Physical Sciences (MPS) Federal Grant Program (CFDA 47.049). This 3-year grant, effective July 1, 2024, supports the development of new biomimetic model systems that imitate the complex behavior of proteins. Professor Marcey Waters at UNC-CH will lead research to determine the molecular features...
North Carolina State University received a $315,105 Project Grant award from the National Science Foundation on August 15, 2021 to complete work by July 31, 2024. The grant funds a collaborative research project to probe coordination specificity of metalloprotein domains with peptide-polymer amphiphile self assembly. This work will be conducted under the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049), which aims to promote progress in these scientific...
This Project Grant from the National Science Foundation Division of Chemistry provides $500,000 to New York University from August 1, 2021 through July 31, 2024 to support research titled "Towards a Greener Approach for Chemical Synthesis of Peptides." The award is part of the Mathematical and Physical Sciences program (CFDA 47.049), which aims to promote progress in these scientific fields and strengthen the national scientific enterprise through increasing knowledge and enhancing...
The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $206,912 Project Grant under the Biological Sciences (CFDA 47.074) program to the University of North Carolina at Chapel Hill. The three-year grant, effective August 1, 2023 through July 31, 2026, supports collaborative research to enhance the understanding of protein structures and behaviors at extreme temperature and pressure conditions. The research aims to develop rules for predicting protein...
The National Science Foundation's Division of Chemistry awarded a $515,013 Project Grant to the University of North Carolina at Chapel Hill to study the reaction chemistry of aromatic building blocks. The grant, which runs from August 1, 2023 to July 31, 2026, supports Professor Jeffrey Johnson's research team as they seek to develop new chemical reactions that generate highly functionalized and useful products from simpler and abundant feedstock chemicals. The research aims to convert...