Project Grant 2304485
- The University of Oklahoma received a $761,727 project grant from the National Science Foundation under the Engineering federal grant program (CFDA 47.041) to support research understanding nanoscale interactions at single-particle and single-cell levels from July 1, 2021 through June 30, 2026. As the awardee, the University will utilize the funding to conduct research and provide data collection services focusing on nanoscale interactions. The NSF Engineering program aims to improve quality...
- The University of Oklahoma received a $107,148 Project Grant award from the National Science Foundation Division of Chemical, Bioengineering, Environmental, and Transport Systems on July 1, 2021 with a completion date of June 30, 2023. The award falls under the NSF Engineering program (CFDA 47.041), which seeks to foster innovation and excellence in engineering research and education. Through this funding, the University of Oklahoma will investigate phonon scattering in superlattices to...
- The University of Oklahoma (OU) was awarded a $1,051,250 Project Grant from the Defense Health Agency to conduct research on the re-expression of miR-195 as a therapeutic strategy for chemoresistant ovarian cancer. This research falls under the Military Medical Research and Development program (CFDA 12.420), which supports biomedical research to transform health care for service members and the American public. The project is scheduled to run from August 15, 2023, to August 14, 2027. As a public...
- The National Science Foundation (NSF) awarded a $568,480 Project Grant under the Engineering (CFDA 47.041) program to The Regents of the University of Colorado, doing business as the University of Colorado, to conduct research on a novel biosensing concept for high-sensitivity measurement of cell mechanical biomarkers. The 3-year award, effective May 1, 2024, will investigate how biological cells with different mechanical properties interact with acoustic waves propagating along a substrate, and...
- The National Science Foundation (NSF) awarded a $500,000 Project Grant to the University of California, San Diego (UCSD) under the Engineering (CFDA #47.041) program to design, fabricate, and evaluate acoustic-to-optical nanoscale transducers. The goal of this 3-year project is to develop novel micro-auscultation devices that can efficiently convert weak sound waves into optical signals, enabling the detection and interpretation of acoustic signatures from small biological objects like cells,...
- The University of Oklahoma's Office of Research Administration is conducting a $314,958 project grant funded by the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049). The project aims to design a microscale device that can extract and quantify nitric oxide (NO) levels in single cells using mass spectrometry. The research seeks to address the challenge of accurately detecting and quantifying the reactive, low-abundance NO molecule in individual cells,...
- Northeastern University was awarded a $398,495 Project Grant from the National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems under the NSF Engineering program (CFDA 47.041). The grant will fund the development of a microfluidic device capable of sorting effective T cells from ineffective T cells for use in cell therapy products. The project aims to improve the biomanufacturing process for engineering immune cell therapies, with a focus on...
- This SBIR Phase I project, funded by a $305,000 award from the National Science Foundation's (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program, aims to develop a microchip-based technology for complex, multidimensional cell reprogramming. The project seeks to create a miniaturized liquid and cell handling system that leverages acoustic-electric micro-vortices to precisely and sequentially deliver genetic molecules, making advanced cell engineering more accessible across...
- This $487,795 award from the National Science Foundation (NSF) Engineering grant program (CFDA 47.041) supports Arizona State University in developing innovative ex vivo models of the tumor microenvironment (TME). The project aims to mechanistically understand how biophysical cues and signaling between stromal and immune cells contribute to the transition of tumor cells into an invasive phenotype, as well as explore how stromal cell function induces pathway signatures in tumor cells leading to...
- The National Science Foundation (NSF) Engineering program (CFDA 47.041) awarded a $134,514 Project Grant to the Board of Regents of the University of Nebraska, operating as the University of Nebraska, to conduct research on "Collaborative Research: Ultrasound Driven Microbubble Clusters for Biomedical Applications" beginning May 1, 2024. The project aims to investigate the relationship between acoustically generated force fields, deformable vessel wall mechanics, and bubble oscillation...
The University of Oklahoma received a $470,184 Project Grant award from the National Science Foundation Division of Chemical, Bioengineering, Environmental, and Transport Systems through the Engineering program (CFDA 47.041) to develop an integrated device for intracellular delivery of molecules into cells. The university will leverage ultrasonic transducers and microfluidic chips to deliver molecules into T cells for adoptive cell transfer cancer immunotherapy. Key products and services include the development of an ultrasonic transducer-microlens complex and microfluidic chip device called the UXUChip for manipulating cells. The university will also investigate the in vitro and in vivo effects of the UXUChip and electroporation on gene and protein expression, cytokine secretion, and the therapeutic potential of engineered T cells in mouse tumor models. The award period is from October 1, 2022 to June 30, 2025.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $470.2k | 2/2/23 |