Project Grant 2302440

Award Date 8/1/23
Completion Date 7/31/27
Dollars Obligated $738K
Funding Federal Agency
Office of Integrative Activities
Federal Grant Program
47.083
Assistance Type
Project Grant
Place of Performance
Atlanta, GA 30310, USA

The National Science Foundation (NSF) Office of Integrative Activities awarded a $738,400 Project Grant to the Morehouse School of Medicine (MSM) to investigate the synergistic effects of engineered extracellular vesicles (EVs) from stem cells and macrophages on angiogenesis, the formation of new blood vessels. The 4-year project will explore how EVs from different cell types cooperatively regulate normal and pathological angiogenesis, as well as develop novel EV-based therapeutic strategies. The award will also support an integrated education plan to increase participation of underrepresented students in science. Key objectives include in vitro and in vivo assessments of the angiogenic effects of the engineered EVs and elucidation of the underlying signaling pathways. The project aligns with NSF's Integrative Activities program, which enhances U.S. research competitiveness and broadens participation in STEM.

Generated 4/30/24, 1:11 PM