Project Grant 2245427

Award Date 1/1/24
Completion Date 12/31/24
Dollars Obligated $500K
Federal Grant Program
47.041
Assistance Type
Project Grant
Place of Performance
Raleigh, NC 27695, USA
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The key products and services to be delivered under this award include: 1) molecular dynamics simulations and interfacial spectroscopy to understand the role of hydration layers in preventing thrombosis, 2) development and fabrication of novel anti-thrombotic coatings based on the simulation and characterization findings, 3) micro-scale evaluation of the blood-material interactions, and 4) integration of the anti-thrombotic coatings and flexible materials at the device-scale. The research will be carried out by a multidisciplinary team with expertise in chemistry, chemical engineering, mechanical engineering, materials science, and biomedical engineering. Sub-awards are planned with the University of Pennsylvania, Georgia Institute of Technology, and the State University of New York to support various aspects of the project.

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