Project Grant 2232948
Award Date
3/1/23
Completion Date
2/28/27
Dollars Obligated
$3.2M
Federal Agency
Division of Integrative Organismal Systems
Federal Grant Program
47.074
Assistance Type
Project Grant
Place of Performance
Ithaca, NY, USA
Similar Awards
This Project Grant award of $279,922 from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) will support the development of new methods to generate diploid gametes in maize, a major crop plant in the U.S. The project aims to enable the inexpensive production of high-yielding hybrid maize seeds through asexual reproduction. The approach involves editing multiple genes involved in cell division and meiosis, as well as leveraging cell division genes from rice. If...
This three-year, $1.8 million project grant from the National Science Foundation Division of Integrative Organismal Systems aims to develop rapid transformation and gene editing techniques in maize through the Biological Sciences program (CFDA 47.074). The University of Missouri System will work to establish a system for precisely inserting transgenes and editing genes at predetermined sites in the genome of maize. Researchers will create "landing pads" on five chromosomes of a...
This $959,997 federal Project Grant, awarded by the National Science Foundation's Biological Sciences program (CFDA 47.074), supports collaborative research at the Cold Spring Harbor Laboratory to develop improved methods for plant transformation and regeneration. The research aims to provide a thorough understanding of the molecular mechanisms underlying regeneration in maize, a key crop that provides a substantial portion of human caloric intake. By exploiting a "morphogenic-based"...
This $322,020 Project Grant award from the National Science Foundation's (NSF) Division of Integrative Organismal Systems will support collaborative research at the University of California, Davis (UC Davis) to develop improved methods for CRISPR/Cas9-based gene editing in maize. The key objectives are to generate maize lines expressing high levels of Cas9 nuclease and to engineer and optimize viral vectors to efficiently deliver guide RNAs for both somatic and heritable gene editing. This...
The National Science Foundation (NSF) awarded a $953,779 Project Grant under the Biological Sciences (CFDA 47.074) program to the Board of Regents of the University of Nebraska to develop innovative data processing and advanced visualization tools for optimizing maize canopy architecture. The goal is to create a "digital twin" of maize plants that can simulate real plant growth and response to the environment. This will allow researchers to experiment with different plant traits and...
This National Science Foundation (NSF) Biological Sciences program grant awarded to New York University (NYU) is titled "EAGER: A GENOME WIDE HDR ENHANCEMENT SCREEN IN MAIZE." The $300,000 award, made on May 1, 2024, funds a 2-year project to develop an efficient method for using CRISPR gene editing technology to transfer stress-tolerant traits between plant varieties. The project aims to identify genes in maize (corn) that can enhance the efficiency of CRISPR-mediated...
This $1,691,891 federal Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports research by the University of California, Irvine into genome evolution and structure in corn (maize). The project aims to investigate how plant genomes can vary substantially in size and organization, yet still produce functional organisms. Specifically, the researchers will measure and compare the folding structures of 25 corn genomes and two related...
This $452,399 federal Project Grant awarded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports research at Hofstra University to investigate the epigenetic regulation of transposable elements in maize. The research aims to study the RNA-directed DNA methylation (RDDM) induced by naturally occurring maize "killer" alleles and explore the dynamic regulation of transposable element silencing in response to developmental cues. The project will...
This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Project Grant award provides $240,000 in funding from January 1, 2025 to December 31, 2027 to investigate the evolutionary dynamics of recombination landscapes and adaptive trait architectures across varying degrees of gene flow. The research will leverage genomic tools, common garden experiments, and evolutionary simulations using the Atlantic silverside fish as a model organism. Key outcomes will include linkage maps to...
This $5 million National Science Foundation Project Grant, awarded under the Biological Sciences program (CFDA 47.074), funds research and educational activities related to leaf angle variation in maize plants from 2022-2026. Iowa State University will lead efforts to identify genes controlling leaf angle variation across plant canopies using high-throughput phenotyping and transcriptomic analyses. Functional validation of candidate genes will be conducted through CRISPR-based gene editing....