Project Grant 2226051
- The University of South Florida (USF) received a $681,876 Project Grant from the National Science Foundation (NSF) Division of Integrative Organismal Systems under the Biological Sciences grant program (CFDA 47.074). The grant will fund a collaborative research project to investigate how prophages (viruses that infect bacteria) influence the structure and function of animal microbiomes, specifically in Ciona robusta (an invertebrate chordate) and Danio rerio (zebrafish). The project will...
- This NSF Biological Sciences (CFDA 47.074) Project Grant award of $600,000 to Emory University will investigate how microbiome communities, which are communities of bacteria and other microbes that live in and on organisms, can resist change and transition to alternate states. The project will use the nematode worm Caenorhabditis elegans as a model host to better define the stability and properties of alternate microbiome states, as well as how factors like antibiotic treatment and host...
- This National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) Project Grant award of $240,000 will fund a 3-year postdoctoral fellowship to research the adaptive response of bacteria to bacteriophage infection and high hydrostatic pressure. The fellow will develop novel fluorescence microscopy techniques to quantify bacterial growth, cell size, and morphology under these environmental stressors using model organisms E. coli, P. aeruginosa, and S. piezotolerans. The project...
- The Regents of the University of Minnesota, through the Office of Sponsored Projects Administration, has received a $200,000 Project Grant award from the National Science Foundation's (NSF) Division of Mathematical Sciences under the Mathematical and Physical Sciences program (CFDA 47.049). The award, effective August 15, 2023 through July 31, 2026, will support collaborative research to characterize the topology and infection dynamics of bacteriophage viruses. Key focus areas include...
- This Project Grant award from the National Science Foundation's (NSF) Division of Molecular and Cellular Biosciences, under the Biological Sciences program (CFDA 47.074), provides $833,999.00 to Georgia Tech Research Corporation (Georgia TECH) to investigate how defined microbiomes respond to viruses over short and long timescales. The project aims to test the hypothesis that robust microbiome functions are promoted by microbial communication systems and costs of virus resistance. This...
- This National Science Foundation Project Grant of $880,632 supports research into drivers and effects of latent phage activation in marine SAR11 bacteria. Funded under the Geosciences program (CFDA 47.050), this three-year award to the University of California, Los Angeles will fill critical knowledge gaps about host-virus interactions in the global oceans. Through field surveys, laboratory experiments, and mathematical modeling, the grantee will quantify the frequency of prophage infections...
- This Project Grant award, funded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074), aims to establish the Drosophila proventriculus as a model system to study symbiotic relationships between insects and their gut microbiomes. The research will identify the specific genes and molecules used by the host to regulate the colonization of symbiotic bacteria, which could have significant implications for understanding and manipulating the relationships between insects...
- This Project Grant award of $270,000 from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) supports a postdoctoral research fellowship investigating the microbial ecology of an extremophile choanoflagellate. The research aims to shed light on how environmental forces shaped the evolutionary emergence of animals from unicellular ancestors. Specifically, the project will study Barroeca monosierra, a recently discovered multicellular choanoflagellate isolated from...
- This Project Grant award, valued at $502,674, was provided by the National Science Foundation's (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program to Minnesota State University Mankato. The funding will support a research project investigating the role of nitrogen source availability in shaping the composition and function of gut microbiomes across different mammalian host species. Key project activities include computationally reconstructing microbial nitrogen transformation networks...
- The National Science Foundation awarded a two-year, $138,000 Project Grant under the Biological Sciences federal grant program (CFDA 47.074) to conduct research characterizing the genetic mechanisms of bacteria-phage coevolution in Listeria and Salmonella. The postdoctoral fellow will analyze the dynamic relationships between the foodborne pathogens Listeria monocytogenes and Salmonella enterica, and their bacteriophages. Through serial passaging experiments and whole genome sequencing, the...
This NSF Biological Sciences program award in the amount of $497,509 to the Regents of the University of Minnesota will support collaborative research on how prophages (viruses that infect bacteria) influence the structure and function of animal microbiomes. The project will utilize the invertebrate chordate Ciona robusta and the vertebrate zebrafish Danio rerio as model systems. The research will integrate genetic, predictive modeling, and experimental approaches to study the biology and ecology of prophages and their impact on animal gut microbiomes. Key goals include characterizing prophage distribution and location in bacterial genomes, determining prophage influence on bacterial host properties, and examining the role of prophages in shaping microbiome colonization and stability. This research aims to reveal general principles by which prophages affect microbial function and microbiome composition. The project will also provide training and mentorship opportunities for students, including those from underrepresented communities, and conduct public outreach through K-12 activities and science festivals.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $497.5k | 8/7/23 |