The National Science Foundation awarded the University of Georgia Research Foundation, Inc. a $299,072 project grant under the Biological Sciences federal grant program (CFDA 47.074). The grant will support comparative single cell transcriptomics and regulomics research from June 2023 to May 2025. Specifically, the foundation will utilize cutting-edge omics techniques to discover the regulatory components of monoterpene indole alkaloid biosynthesis in two plant species. Researchers will...
This National Science Foundation Project Grant award of $510,734 supports research at the University of Wyoming to develop genetically engineered bacterial systems for enhanced biodiesel production from lignocellulosic feedstocks. The goal is to program bacterial cells to produce high quantities of triacylglycerol (TAG), a commodity chemical that can be converted to biodiesel and industrial solvents. Specifically, the award will fund work to transform Rhodococcus strains into multicellular...
This National Science Foundation (NSF) Project Grant under the CFDA program "Biological Sciences" (47.074) is awarded to Trustees of Boston University to develop and optimize optogenetic tools for selecting bacterial cells based on dynamic, time-varying traits. The $796,158 award, effective August 1, 2023 through July 31, 2026, supports the researchers in creating light-inducible genetic constructs that trigger antibiotic resistance, enabling the isolation of bacteria exhibiting...
The National Science Foundation (NSF) awarded a $9,500,000 Cooperative Agreement to the University of Georgia Research Foundation, Inc. under the Biological Sciences (CFDA 47.074) program. The "BIOFOUNDRY: GLYCOSCIENCE RESOURCES, EDUCATION, AND TRAINING (BIOF:GREAT)" project aims to develop new research tools, technologies, and instructional resources to enable broader adoption of glycoscience into research and education. Key focus areas include: 1) bioinformatic tools and machine...
This Project Grant award of $575,765, provided by the National Science Foundation (NSF) Engineering program (CFDA 47.041), supports research at Northeastern University to enhance the production of biochemicals from sustainable single-carbon (C1) feedstocks using acetogenic bacteria. The key objectives are to 1) understand the metabolic and regulatory mechanisms by which acetogens leverage multiple substrates simultaneously to overcome growth limitations, and 2) apply this knowledge to direct...
The National Science Foundation (NSF) awarded a $2,668,807 Project Grant under the Biological Sciences program (CFDA 47.074) to the Georgia Tech Research Corporation (Georgia Tech) to develop "biopebbles" - natural polymer particles that can enhance nitrogen fixation by soil bacteria, thereby reducing dependency on synthetic fertilizers and their harmful environmental effects. The project will utilize principles of materials science and bioengineering to create the biopebbles, which...
The National Science Foundation Division of Integrative Organismal Systems awarded $240,063 to Georgia Tech Research Corporation under a Project Grant titled "COLLABORATIVE RESEARCH: RUI: IMPLICATIONS OF BACTERIALLY DRIVEN CROSS-KINGDOM CHEMICAL INTERACTIONS." The grant period runs from May 15, 2021 through April 30, 2024. The funding supports research into major problems confronting the nation under the Biological Sciences program (CFDA 47.074). Specifically, the grant aims to...
This Project Grant award of $275,000, funded by the National Science Foundation (NSF) under the CFDA program 47.084 "NSF Technology, Innovation, and Partnerships", aims to develop improved bacterial strains for more cost-effective production of proteins used in detergents, personal care products, and dairy. The project seeks to identify superior bacterial hosts and develop advanced genetic engineering tools to convert these bacteria into efficient protein factories. The goal is to...
This Project Grant award from the National Science Foundation (NSF) under the Biological Sciences program (CFDA 47.074) provides $369,297 to San Francisco State University (SFSU) to develop a synthetic transhydrogenation module to enhance the production of valuable chemicals using engineered organisms. The key objectives are to: Elucidate the structural mechanisms underlying the autoregulation of the GltAB-GudB enzyme complex in Bacillus subtilis, which regulates glutamate metabolism and impacts...
This three-year, $370,330 Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports characterizing rhizosphere decomposition through novel techniques in contrasting salt marshes. The University of Georgia Research Foundation will employ methods to advance understanding of major problems in the biological sciences, such as decomposing plant material and nutrient cycling near root zones. Work will take place in Athens, Georgia from December 2021...