The National Science Foundation awarded a $216,000 Project Grant to support research titled "The Role of Vegetative Development on Plant Response to Environmental Stress from Genomic and Physiological Perspectives" from February 1, 2022 to January 31, 2025 under the Biological Sciences program (CFDA 47.074). The three-year award will fund postdoctoral research at the University of Pennsylvania in Philadelphia exploring how plant vegetative development influences responses to...
The Trustees of the University of Pennsylvania received a $526,084 Project Grant from the National Science Foundation Division of Integrative Organismal Systems. The grant is part of the Biological Sciences program (CFDA 47.074) to promote progress in the biological sciences. Under the award, the University will conduct collaborative research to predict plant phenotypes from molecular profiles using topological data analysis and deep learning. Researchers will use X-ray computed tomography to...
This $804,525 project grant from the National Science Foundation's Division of Molecular and Cellular Biosciences, under the Biological Sciences program (CFDA 47.074), will fund research exploring the epigenetic mechanisms by which ultraviolet B radiation alters DNA methylation patterns in plants. Specifically, the University of Missouri-St. Louis will investigate how UVB exposure and its photoreceptor interact to change locus- and tissue-specific DNA methylation in Arabidopsis thaliana, and how...
This Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences (CFDA 47.049) program provides $200,000 in funding to The Trustees of the University of Pennsylvania to conduct collaborative research that aims to understand genomic organization in the cell nucleus. The research team will employ an integrated approach leveraging biophysical modeling, super-resolution imaging, and machine learning to develop predictive models of how chromatin structure and...
The National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) awarded a $810,001 project grant to The Trustees of the University of Pennsylvania to study the role of N6-methyladenosine (m6A) modifications in regulating plant gene expression and response to bacterial pathogens. The 4-year project aims to characterize the addition and removal of m6A on plant RNAs and investigate how these epitranscriptomic processes impact a plant's ability to recognize and respond to...
This Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) provides $300,000 in funding to Western University of Health Sciences to conduct collaborative research on the variability and regulation of the plant polyadenylation complex. The research aims to better understand how this complex mediates gene expression and plant responses to environmental and developmental cues, with the goal of improving our knowledge of crop plant growth,...
This $999,999 Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) will fund research at the Donald Danforth Plant Science Center to elucidate the mechanisms initiating de novo chromatin modification cycles in plant cells. Over three years, the award will support experiments using cutting-edge techniques to dissect the molecular triggers establishing heritable DNA methylation patterns and long-term epigenetic silencing of transposable elements and...
The Pennsylvania State University received a $1.8 million Project Grant award from the National Science Foundation Division of Integrative Organismal Systems. The award is for the project "COLLABORATIVE RESEARCH: RESEARCH-PGR: GENETIC AND ENVIRONMENTALLY-INDUCED FUNCTIONAL VARIATION IN THE RICE RNA STRUCTUROME" under the Biological Sciences program (CFDA 47.074). The project aims to advance understanding of major problems in biological sciences by investigating genetic and...
The Trustees Of The University Of Pennsylvania received a $875,000 Project Grant award from the National Science Foundation Division of Environmental Biology. The grant funds research on "The Evolutionary Significance of Genetic Pleiotropy in Species Interactions" from September 1, 2021 through August 31, 2024. The research aims to advance understanding of major problems in biological sciences, as outlined in the Biological Sciences program (CFDA 47.074) of the National Science...
This two-year, $1,204,512 National Science Foundation project grant supports research into the robustness and adaptability of the dynamic epigenome through a multiscale approach. Funded under the Biological Sciences program (CFDA 47.074), the award to Brandeis University involves investigating the fundamental rules that guide adaptive epigenetic changes in cells without alterations to the genetic blueprint. The research utilizes high-resolution imaging, microfluidics, and automated culture...