The National Science Foundation (NSF), through its Mathematical and Physical Sciences (CFDA 47.049) program, awarded a $117,562 Project Grant to Worcester Polytechnic Institute (WPI) to develop a class of bioadhesive implants using a modular design. The bioadhesive implants integrate a liquid adhesive polymer layer and a solid hydrogel layer to provide fast, stable, and strong adhesion to target tissues while matching their mechanical properties. This research aims to address challenges with...
This $200,000 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) supports a collaborative research effort led by New York University (NYU) School of Medicine. The project aims to enhance the design of fluorinated protein fibers and hydrogels for medical applications. Key objectives include: 1) generating coiled-coil fluorinated fibers for controlled drug delivery, 2) developing temperature-responsive fluorinated hydrogels,...
This $424,389 federal Project Grant awarded by the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) supports the development of a novel modular injectable hydrogel design based on polymeric micelles with thermosensitive patchy domains. The research aims to establish design criteria for these thermosensitive hydrogels that can provide controlled mechanical properties, dissolution profiles, and the ability to incorporate bioactive motifs. Key products...
The National Science Foundation (NSF) awarded Rensselaer Polytechnic Institute (RPI) a $461,594 Project Grant under the Mathematical and Physical Sciences (CFDA #47.049) program. The 3-year grant, running from September 1, 2024 to August 31, 2027, will support research to advance the understanding of polymer gels, an important class of materials used in a variety of health, industrial, and defense applications. The project aims to correlate spatiotemporal fluctuations of individual polymer...
This Project Grant award for $145,598, provided by the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) program, supports the development of peptide-based, stimuli-responsive biomaterials for wound healing and drug delivery applications. The principal investigator at Baylor University will design three classes of self-healing, antimicrobial hydrogels that change stiffness in response to changes in redox state and pH. This research aims to generate...
This National Science Foundation (NSF) Project Grant award to Rensselaer Polytechnic Institute (RPI), with a CFDA program title of "Engineering" (47.041), provides $150,027 to develop a new class of fiber-reinforced plastic (FRP) materials based on vitrimers. The project aims to overcome challenges with damage and poor recyclability of FRPs used in high-performance applications like aerospace and automotive by enabling the reversal of fatigue-induced damage through periodic heating....
This National Science Foundation (NSF) Division of Materials Research Project Grant, CFDA# 47.049 Mathematical and Physical Sciences, provides $400,000 in funding to The Trustees of the University of Pennsylvania to conduct collaborative research on developing novel hybrid metal-piezoelectric biomaterials for anti-infectious implantable medical devices. The key objective is to create advanced multifunctional biomaterial platforms that can effectively prevent biofilm formation and bacterial...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $151,559 to Rensselaer Polytechnic Institute (RPI) from August 3, 2024 to July 31, 2026. The project aims to develop innovative magnetically responsive drug delivery electrospun fibers to improve regeneration after spinal cord injury (SCI). Specifically, the research will focus...
This $199,988 National Science Foundation Engineering Research Initiation award will support the development of a 3D in vitro model to study the relationship between changes in brain tissue extracellular matrix composition and neuroinflammation. Specifically, the awardee, Trinity University, will fabricate multi-interpenetrating polymer networks comprised of fibrin, hyaluronic acid, collagen, and polyethylene glycol to mimic key changes in matrix content and study their effect on human astrocyte...
The National Science Foundation awarded a $750,000 Project Grant to Rutgers, The State University under the Engineering program (CFDA 47.041) from September 1, 2022 to August 31, 2025. The grant funds research to develop an injectable nanoparticle therapy to restore strength and length to damaged tendons and ligaments. Specifically, the university will investigate combining a thermosensitive polymer and crosslinking agent to stabilize joints by quickly strengthening and returning tissues like...