Project Grant 2214012
- Insoma Bio, Inc. received a $252,992 National Science Foundation Engineering Division Project Grant to develop an injectable protein matrix to enhance the stability of autologous fat grafts. The goal of the one-year grant project, which runs from July 2021 through June 2022, is to create a biocompatible hydrogel scaffold for adipose tissue engineering that can improve the survival rate of fat transfer procedures. The NSF Engineering Division seeks to foster innovation in engineering research...
- This $256,000 Project Grant from the National Science Foundation's Technology, Innovation, and Partnerships program will support the development of additive manufacturing techniques for soft tissue repair. Asante Bio LLC will receive funding to design and engineer a novel 3D microfiber printer capable of assembling synthetic biopolymer filaments into fibrous, flexible implants that promote soft tissue healing. Through this six-month award ending November 2022, Asante Bio will optimize...
- This $300,000 project grant from the National Science Foundation will fund research at Cornell University from October 1, 2022 to September 30, 2025. The award is provided through NSF's Engineering Biology and Health Cluster within the Directorate for Engineering, Biological Sciences and Biotechnology, under the CFDA program for Engineering. Specifically, researchers at Cornell University and Washington State University will work to develop new tissue engineering strategies for cartilage repair....
- The National Science Foundation awarded a $750,000 Project Grant to Rutgers, The State University under the Engineering program (CFDA 47.041) from September 1, 2022 to August 31, 2025. The grant funds research to develop an injectable nanoparticle therapy to restore strength and length to damaged tendons and ligaments. Specifically, the university will investigate combining a thermosensitive polymer and crosslinking agent to stabilize joints by quickly strengthening and returning tissues like...
- This federal Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) provides $424,389 to The Pennsylvania State University to develop novel thermosensitive hydrogel materials with enhanced design flexibility and controllable properties. The project aims to create a new class of thermogelling hydrogels using polymeric nanoparticles that form "sticky" patches at body temperature, enabling the formation of well-defined...
- This $500,000 project grant from the National Science Foundation Division of Civil, Mechanical, and Manufacturing Innovation supports research titled "GOALI/COLLABORATIVE RESEARCH: INSTABILITIES AND LOCAL STRAINS IN ENGINEERED CARTILAGE SCAFFOLD" being conducted at Cornell University from January 1, 2022 to December 31, 2024. The research aims to improve understanding of instabilities and local strains in engineered cartilage scaffolds, with the goal of enabling innovation in cartilage...
- This National Science Foundation Project Grant of $100,000 supports research into polyelectrolyte multilayered surfaces for use in human mesenchymal stem/stromal cell manufacturing. The goal is to develop a scalable and controllable polymeric coating composed of natural polymers to improve the cell expansion process used in producing therapeutic human mesenchymal stromal cells. The coating is constructed via layer-by-layer assembly of collagen and heparin and has been shown to increase cell...
- This three-year, $1.2 million project grant from the National Science Foundation's Engineering program (CFDA 47.041) will support research at Washington State University and Cornell University to develop new tissue engineering strategies for cartilage regeneration. The researchers aim to stimulate adult stem cells to become mature chondrocytes for cartilage production through small molecules that interfere with bone cell differentiation genes. Real-time imaging will monitor cell growth...
- This $235,977 Project Grant awarded by the National Science Foundation (NSF) under the Integrative Activities program (CFDA 47.083) will support a collaboration between the University of Maine (UMaine) and the Molecular Foundry at Lawrence Berkeley National Laboratory to develop a new class of biomimetic hydrogel materials for tissue engineering and stem cell therapy applications. The key objectives are to: 1) synthesize a library of functionalized peptoid conjugates capable of forming...
- This $476,886 federal Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) supports research at Boston University to develop computational models for predicting the spatiotemporal distribution of growth factors in tissue engineering scaffolds. The goal is to optimize scaffold designs to achieve optimal growth factor exposure profiles that improve tissue regeneration outcomes, particularly for cartilage repair. The research utilizes reaction-diffusion...
This $516,000 Project Grant from the National Science Foundation's Technology, Innovation, and Partnerships program will support the development of injectable cellulose-based hydrogels for soft tissue bulking from July 1, 2022 to June 30, 2024. The Research Foundation of the City University of New York, in partnership with the City University of New York, will engineer a stable yet reversible injectable soft tissue filler material derived from plant polysaccharides like cellulose. If successful, this could provide a low-cost alternative to the over $395 million annually spent in the U.S. on semi-permanent tissue fillers and fat grafts with unsatisfactory results. The researchers aim to demonstrate the safety and efficacy of these plant-derived biomaterials in restoring soft tissue deficits in a small animal model, laying the groundwork for future human clinical trials of a potentially transformative technology for soft tissue reconstruction.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $16.0k | 12/21/22 | ||
| Not listed | $250.0k | 6/13/22 |