This $174,769 National Science Foundation Project Grant supports the acquisition of a high-pressure stopped-flow spectrophotometer/fluorimeter system at Rensselaer Polytechnic Institute. The instrument, the first of its kind in the U.S., will be housed in RPI's Analytical Biochemistry Core Facility to study biological systems under extreme conditions. It will enable research on the effects of high hydrostatic pressure on biological macromolecules and enzyme kinetics, furthering understanding of molecular adaptation in extremophilic organisms. The instrument will also support hands-on workshops for undergraduate and graduate students from RPI and other institutions. Funded through the NSF Biological Sciences program, which aims to advance biological knowledge and understanding of major problems through basic research, this award reflects the Foundation's goals of intellectual merit and broader impacts.
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