Project Grant 2212222
- Nano Pharmasolutions, Inc. received a $275,961 Project Grant award from the National Science Foundation Division of Industrial Innovation under the Engineering federal grant program (CFDA 47.041). The grant funds the development of a novel nanoformulation drug delivery platform to address challenges associated with poorly soluble drugs. The goal is to improve drug solubility and bioavailability through innovative formulation approaches. The one-year project period runs from August 1, 2021...
- The National Science Foundation awarded Diant Pharma Inc. a $256,000 Project Grant under the Engineering (47.041) federal grant program. The grant will support development of an advanced continuous manufacturing system for nucleic acid lipid nanoparticles to improve supply chains for therapeutics and vaccines. Specifically, the small business innovation research Phase I project aims to create a compact, end-to-end manufacturing platform that follows current good manufacturing practices. This...
- The National Science Foundation (NSF) awarded a $1,247,672 Cooperative Agreement to Superior Nano LLC under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program. The project aims to develop the first insulin pill for diabetes patients, leveraging lipid nanoparticle technology to improve insulin absorption and shelf stability. This builds on prior Phase I SBIR funding that demonstrated the concept of encapsulating insulin in lipid nanoparticles. The proposed work focuses on...
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Delaqua Pharmaceuticals, Inc. aims to enhance the therapeutic use of hydrophobic drugs through a polymeric micelle approach to drug solubilization. The key objectives are to 1) improve the formulation of spherical micelles for enhanced stability and drug solubilization, 2) perform initial toxicity studies to establish the safety of the platform, and 3) demonstrate...
- Nostopharma LLC was awarded a $256,000 Small Business Technology Transfer Phase I Project Grant from the National Science Foundation to develop a sustained-release, biodegradable nanoparticle drug delivery system for treatment of soft tissue trauma complications. Funded under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084), the 12-month project beginning March 1, 2022 aims to demonstrate in vitro and in vivo feasibility of modulating the ectopic bone microenvironment...
- Spherofill LLC received a $275,391 National Science Foundation Project Grant under the Engineering program (CFDA 47.041) to develop Porous Walled Hollow Glass Microspheres as a novel sustained drug delivery platform. The one-year award running from June 2021 to May 2022 will support Phase I of Small Business Technology Transfer research into PWHGMs, a flexible platform capable of customized drug release profiles. As part of its mission to promote innovation, the NSF Directorate for Engineering...
- This Project Grant award from the National Science Foundation (NSF) under the Mathematical and Physical Sciences program (CFDA 47.049) provides $272,799 to South Dakota State University to conduct collaborative research on the development and mechanistic studies of microenvironment-sensitive polymeric nanoparticles. The objective is to create nanometer-scale polymeric particles that can deliver therapeutics to target areas while also enhancing ultrasound imaging capabilities. The research team...
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Phase I Small Business Innovation Research (SBIR) award of $274,947 to Lattice Therapeutics Inc. supports the development of a customizable, next-generation RNA delivery particle. The project aims to validate the ability of an engineerable protein nanoparticle platform to efficiently and specifically deliver RNA cargoes to target cancer cells. Key objectives include in vitro evaluation of RNA...
- The National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a $232,000 Project Grant to the President and Board of Trustees of Santa Clara College to develop an active lipid vesicle-based drug delivery system. The 3-year grant, starting on September 1, 2023, will leverage the encapsulation capacity of lipid vesicles to enclose both therapeutic payloads and self-propelled particles. This will enable the vesicles to undergo directed...
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Om Therapeutics Inc. will support the development of a system to enable the rapid, scalable, and cost-effective discovery of new medicines using machine learning. The project aims to encapsulate proteins and small molecules in millions of miniaturized compartments to screen for interactions that could identify novel drug candidates. The key innovations include...
Superior Nano LLC received a $512,000 National Science Foundation Project Grant to develop dense nanolipid fluid systems for delivering drugs with poor bioavailability. The NSF funding supports research from June 2022 to May 2023 under the Technology, Innovation, and Partnerships program. This award will allow Superior Nano to advance scientific understanding of surfactant-lipid-water systems and create new knowledge applicable to manufacturing drug nanoparticles using twin-screw extrusion. By exploring transient mesophase formation during extrusion, the company aims to enable scalable, low-cost production of lipid nanoparticles for improving drug absorption. If successful, this research could help translate lipid-based drug delivery into clinical use by overcoming limitations of cost and reproducibility that currently impede widespread application. The project aligns with NSF's mission to support technological innovation addressing national needs.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $256.0k | 6/17/22 |