Project Grant 2203613
- The National Science Foundation (NSF) awarded a $432,000 Project Grant under the Mathematical and Physical Sciences (CFDA 47.049) program to the University of Utah. The funding supports a research project led by Professor Jon Rainier that aims to utilize light-driven photoelectrocyclization reactions to synthesize complex, optically active molecules with potential pharmaceutical, agricultural, and materials applications. The project seeks to uncover fundamental photochemical phenomena and...
- Federal Grant Award Summary The National Science Foundation's Division of Chemistry has awarded the University of Utah $639,000 under the Mathematical and Physical Sciences program (CFDA 47.049) for the project "Chemical Toolkit for Monitoring and Modulating Receptor Tyrosine Phosphatase Activity." The award, initiated September 1, 2025, and extending through August 31, 2028, supports a collaborative research effort led by Professor Amy Barrios at the University of Utah and Professor...
- This National Science Foundation project grant of $221,000 supports research into photoelectrocyclization reactions to develop anti-inflammatory natural products. Awarded under the Mathematical and Physical Sciences program (CFDA 47.049), the University of Utah team led by Dr. Andrew Roberts will study the generation and structural elaboration of small molecule anti-inflammatory agents using electrocyclization reactions on readily available precursors. Specifically, the team will develop and...
- The National Science Foundation (NSF) Division of Chemistry awarded a $420,000 Project Grant to the University of Utah from August 1, 2023 to July 31, 2026 under the Mathematical and Physical Sciences program (CFDA 47.049). The funding supports the development of a novel optical biosensor capable of detecting and quantifying a wide range of biological molecules, including biomarkers found in bodily fluids. The project leverages second harmonic generation (SHG) and optical heterodyning techniques...
- The University of Utah will use a $550,000 Project Grant from the National Science Foundation Division of Chemistry to examine thermochemistry of metal-ligand bonds and protonated peptides from June 15, 2023 to May 31, 2026. The work falls under the NSF Mathematical and Physical Sciences program (CFDA 47.049), which aims to advance scientific knowledge and understanding in these fields. Professor Peter B. Armentrout and his research group will utilize guided ion beam tandem mass spectrometry...
- This $447,000 Project Grant from the National Science Foundation's Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), will support research at Haverford College from December 2022 through February 2026. The research team, led by Dr. Louise Charkoudian, will investigate type II polyketide biosynthetic enzyme assemblies across bacterial species to leverage their capabilities for sustainable chemical production. Undergraduate students will gain research...
- This $440,262 federal Project Grant award was provided by the National Science Foundation (NSF) Division of Chemistry under the Mathematical and Physical Sciences (CFDA 47.049) grant program. The award supports a collaborative research project between professors at the Georgia Institute of Technology and Utah State University to study the evolution of archaeal protein tyrosine phosphatases (PTPs), a family of enzymes crucial for cellular signaling processes. The research aims to quantitatively...
- The National Science Foundation Division of Chemistry awarded $550,000 to the University of Utah under the Mathematical and Physical Sciences federal grant program (CFDA 47.049) to support research transforming amines into complex polycyclic molecules and natural products from June 1, 2023 to May 31, 2026. Professor Andrew G. Roberts and his research team will develop new synthetic methodology using tertiary amines as templates to iteratively form carbon-nitrogen and carbon-carbon bonds,...
- Federal Project Grant Award Summary Under this $600,000 Project Grant awarded by the National Science Foundation's Division of Chemistry through the Mathematical and Physical Sciences program (CFDA 47.049), Professor Matthew Sigman of the University of Utah will conduct fundamental research into heteroleptic metal complex catalysts from October 1, 2025, through September 30, 2028. The primary deliverables include the development of novel catalytic strategies that employ data science...
- This $597,945 federal Project Grant awarded by the National Science Foundation's (NSF) Division of Chemistry under the Mathematical and Physical Sciences (CFDA 47.049) program supports research by Tobias W. Giessen at the University of Michigan, Ann Arbor to investigate the structure and function of peptide-modifying enzyme filaments found in bacteria and archaea. The proposed work will generate new insights into the self-assembly and catalytic activity of these filamentous enzymes, which...
This Project Grant from the National Science Foundation Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), provides $1,445,996 to the University of Utah from July 1, 2022 to June 30, 2025. The funding supports research by Drs. Eric Schmidt and Chris Hill to characterize the structure and function of novel polyketide synthases found in mammalian biology, including human biology. The researchers will use biochemical methods like kinetic analysis and cryo-electron microscopy to determine the structures of the mammalian polyketide synthases and the novel lipid products they produce. They will also conduct mutational analyses informed by the structural studies. This work aims to establish the structural principles governing substrate and product selectivity in mammalian polyketide synthases. Additionally, the Schmidt and Hill team will engineer new lipid derivatives by comparing results from the mammalian systems research to those from studies of human fatty acid synthase. The award also supports postdoctoral fellow training and a summer program introducing structural biology to high school students.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $723.0k | 6/6/22 |