Project Grant 2154353
- The National Science Foundation (NSF) awarded a $432,000 Project Grant under the Mathematical and Physical Sciences (CFDA 47.049) program to the University of Utah. The funding supports a research project led by Professor Jon Rainier that aims to utilize light-driven photoelectrocyclization reactions to synthesize complex, optically active molecules with potential pharmaceutical, agricultural, and materials applications. The project seeks to uncover fundamental photochemical phenomena and...
- This Project Grant from the National Science Foundation Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), provides $1,445,996 to the University of Utah from July 1, 2022 to June 30, 2025. The funding supports research by Drs. Eric Schmidt and Chris Hill to characterize the structure and function of novel polyketide synthases found in mammalian biology, including human biology. The researchers will use biochemical methods like kinetic analysis and...
- Professor Kutateladze of the University of Denver will use a $575,000 National Science Foundation Project Grant from the Mathematical and Physical Sciences program (CFDA 47.049) to further develop photoassisted approaches for the synthesis of complex heterocyclic molecules with potentially useful therapeutic properties. Over a three-year period from September 2023 through August 2026, his research aims to expand the synthetic photochemistry toolbox, specifically excited state intramolecular...
- The National Science Foundation Division of Chemistry awarded $550,000 to the University of Utah under the Mathematical and Physical Sciences federal grant program (CFDA 47.049) to support research transforming amines into complex polycyclic molecules and natural products from June 1, 2023 to May 31, 2026. Professor Andrew G. Roberts and his research team will develop new synthetic methodology using tertiary amines as templates to iteratively form carbon-nitrogen and carbon-carbon bonds,...
- The National Science Foundation Division of Chemistry awarded a $537,452 Project Grant to the University of Arizona under the Mathematical and Physical Sciences program (CFDA 47.049) to develop new light-promoted chemical reactions for studying the biological role of the mitochondrial translocator protein tryptophan-rich sensory protein (TSPO). Over a three-year period from November 1, 2022 to December 31, 2025, Dr. Michael Taylor will design photoactivatable probes and conjugation reactions...
- The University of Utah received a $600,000 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) to study new strategies for organometallic reaction development using data science tools and heteroleptic catalysts. Under this 3-year project, Professor Matthew Sigman's research group will investigate the reactivity, mechanism, and synthetic applications of heteroleptic metal complex catalysts that require two disparate ligand...
- The National Science Foundation (NSF) Division of Chemistry awarded a $420,000 Project Grant to the University of Utah from August 1, 2023 to July 31, 2026 under the Mathematical and Physical Sciences program (CFDA 47.049). The funding supports the development of a novel optical biosensor capable of detecting and quantifying a wide range of biological molecules, including biomarkers found in bodily fluids. The project leverages second harmonic generation (SHG) and optical heterodyning techniques...
- This Project Grant award of $510,759 from the National Science Foundation (NSF) Division of Chemistry supports a research collaboration led by Professors Andrew Mitchell of Illinois State University and Dean Tantillo of UC-Davis. The goal is to develop new chemical reactions with connections to biology, medicine, physics, materials, and environmental sustainability. Key products include: Advancing oxidopyrylium-based [5+2] cycloaddition reactions to construct important heterocyclic small...
- This $550,000 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences Program (CFDA 47.049) supports research by Professor Anna D. Gudmundsdottir of the University of Cincinnati on the photodynamic and mechanical properties of crystalline compounds. The research team will investigate how benzoyl peroxide, alkyl- and aryl-azide derivatives respond to light exposure, including dramatic effects like dissociation, fracturing, and color changes. This...
- This $688,144 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences (CFDA 47.049) program supports a collaborative research effort led by Professors Ilya Zharov and John Conboy of the University of Utah. The project aims to elucidate the molecular-level interactions between polymer-grafted silica nanoparticles during self-assembly using sum frequency generation (SFG) vibrational spectroscopy. The researchers will systematically investigate how...
This National Science Foundation project grant of $221,000 supports research into photoelectrocyclization reactions to develop anti-inflammatory natural products. Awarded under the Mathematical and Physical Sciences program (CFDA 47.049), the University of Utah team led by Dr. Andrew Roberts will study the generation and structural elaboration of small molecule anti-inflammatory agents using electrocyclization reactions on readily available precursors. Specifically, the team will develop and optimize chemistry converting bis- and mono-arylcyclobutenones from cross-coupling reactions into complex polycyclic systems using sustainable light-based reagents. In addition to advancing the scientific understanding of excited state reactivity and trapping reactive intermediates, this research is expected to help train next-generation scientists and provide a creative route to important anti-inflammatory drug scaffolds. The award period is August 1, 2022 through July 31, 2024.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $221.0k | 7/26/22 |