Project Grant 2155215

Award Date 9/1/22
Completion Date 8/31/25
Dollars Obligated $500K
Federal Grant Program
47.049
Assistance Type
Project Grant
Place of Performance
Fort Collins, CO 80521, USA
Similar Awards
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) provides $259,966.00 to Colorado State University to develop new synthetic strategies to functionalize pyridine and diazine heterocycles. The key objectives are to: 1) Install heterocyclic phosphonium salts and exploit their reactivity for coupling reactions with various nucleophiles, 2) Utilize NTF-pyridinium salts for direct...
This $650,000 Project Grant awarded by the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) funds an industrial-academic collaboration between Princeton University and the Merck Catalysis Laboratory. The goal is to develop new sustainable catalytic methods for the large-scale synthesis of pharmaceutical drugs using earth-abundant metals like iron, cobalt, and nickel instead of rare precious metals. The research aims to identify viable catalytic...
Colorado State University Sponsored Programs Division was awarded a three-year $406,500 Project Grant from the National Science Foundation's Mathematical and Physical Sciences program to develop chemical tools to investigate phosphatidylinositol mannosides (PIMs) in the Corynebacterineae suborder of bacteria. Under the award beginning July 1, 2023, Professors Benjamin Swarts of Central Michigan University and Mary Jackson of Colorado State University will synthesize carbohydrate-based probes...
This National Science Foundation (NSF) Mathematical and Physical Sciences Program (CFDA 47.049) project grant of $800,000 awarded to the University of Illinois at Urbana-Champaign supports research on developing new methods for catalyzing the synthesis of high-value heterocyclic ring systems that are prominent in pharmaceuticals, natural products, and agrochemicals. The 4-year project, led by Professor Scott E. Denmark, aims to leverage selenium-based catalysts to anneal doubly functionalized...
This $700,000 Project Grant, awarded by the National Science Foundation's (NSF) Mathematical and Physical Sciences Program (CFDA 47.049), supports a collaborative research effort led by professors at the University of Wisconsin-Madison, University of Missouri-Kansas City, and Colorado State University. The project aims to develop new analytical and computational tools to study the fundamental principles underlying nickel-catalyzed, electrochemically-driven biaryl synthesis - a process for...
The National Science Foundation Division of Chemistry awarded $550,000 to the University of Utah under the Mathematical and Physical Sciences federal grant program (CFDA 47.049) to support research transforming amines into complex polycyclic molecules and natural products from June 1, 2023 to May 31, 2026. Professor Andrew G. Roberts and his research team will develop new synthetic methodology using tertiary amines as templates to iteratively form carbon-nitrogen and carbon-carbon bonds,...
North Carolina State University will receive $1,050,000 from the National Science Foundation under the Mathematical and Physical Sciences program (CFDA 47.049) to develop novel methods for synthesizing nitrogen heterocycles. Principal Investigator Joshua Pierce will lead research into new preparation approaches for five-membered nitrogen-containing ring structures using [3+2]-cycloaddition reactions. Three specific areas will be investigated: 1) allene/alkene and 1,3-dipolar cycloadditions...
This $575,000 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) supports a collaborative research project led by Professors Keary Engle of the Scripps Research Institute and Peng Liu of the University of Pittsburgh. The project focuses on developing new chemical reactions using earth-abundant nickel catalysts to efficiently synthesize valuable compounds, including medicinally relevant molecules, agrochemicals, and functional...
The National Science Foundation Division of Chemistry awarded a $1,050,000 Project Grant to the Scripps Research Institute under the Mathematical and Physical Sciences federal grant program (CFDA 47.049) to support research exploring attached-ring cross-coupling chemistry and its applications. Over a three-year period from August 1, 2022 to July 31, 2025, Professor Ryan Shenvi of Scripps Research Institute will develop new non-precious metal reagents and methods for concise syntheses of...
Professor Kutateladze of the University of Denver will use a $575,000 National Science Foundation Project Grant from the Mathematical and Physical Sciences program (CFDA 47.049) to further develop photoassisted approaches for the synthesis of complex heterocyclic molecules with potentially useful therapeutic properties. Over a three-year period from September 2023 through August 2026, his research aims to expand the synthetic photochemistry toolbox, specifically excited state intramolecular...

The National Science Foundation Division of Chemistry awarded Colorado State University $500,000 under the Mathematical and Physical Sciences federal grant program (CFDA 47.049) to develop new methods for piperidine synthesis using Zincke imine intermediates. Through a collaboration with Merck, CSU researchers Andrew McNally and Matthew Maddness will work to establish fundamental reaction pathways to efficiently convert planar pyridines to substituted piperidines, an important class of pharmaceutical agents. Merck will provide its high-throughput experimentation and artificial intelligence technologies to facilitate achievement of project goals. The award will support graduate student training and provide experience with Merck technologies. If successful, the research could yield new transformations enabling access to three-dimensional scaffolds and atropisomeric piperidine derivatives, offering an entirely new route to such axially chiral systems.

Generated 1/6/24, 7:26 PM