This $228,806 Project Grant from the National Science Foundation Division of Mathematical Sciences, under the Mathematical and Physical Sciences program (CFDA 47.049), will support collaborative research between the University of Houston and Baylor College of Medicine to develop comprehensive mathematical models of respiratory muscles, with a focus on the diaphragm. The research aims to improve understanding of diaphragm mechanics and generate analytical tools to quantify diaphragm performance. Specifically, the grant will fund development of constitutive theories for respiratory muscle modeling, continuum mechanics theories to model large diaphragm deformations, equations of motion governing diaphragm shape and stress under muscle activation and pressures, in vitro experiments, and validation of computational models against experimental data. Project results are expected to increase physiologic understanding of respiratory muscle function in health and disease. The grant period is from August 1, 2022 to July 31, 2025 and all work will be conducted at the University of Houston in Houston, Texas.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $228.8k | 7/13/22 |