This Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) provides $2,379,217 to the Donald Danforth Plant Science Center from March 1, 2022 to February 28, 2025. The grant supports research to develop targeted DNA integration techniques in plants. Specifically, the Center and its sub-awardees—the University of South Carolina Aiken Campus and University of Missouri—will work to engineer hyperactive versions of the Pong transposase proteins and...
The National Science Foundation Division of Integrative Organismal Systems awarded a $375,000 Project Grant to the Donald Danforth Plant Science Center for research titled "NOVEL ANTIFUNGAL SYMBIOTIC PEPTIDES: MODES OF ACTION AND CONTROL OF FUNGAL PATHOGENS." The three-year award beginning June 1, 2021 will fund research under the Biological Sciences program (CFDA 47.074) to investigate modes of action and control of fungal pathogens through novel antifungal symbiotic peptides. The...
This $999,999 Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) will fund research at the Donald Danforth Plant Science Center to elucidate the mechanisms initiating de novo chromatin modification cycles in plant cells. Over three years, the award will support experiments using cutting-edge techniques to dissect the molecular triggers establishing heritable DNA methylation patterns and long-term epigenetic silencing of transposable elements and...
This National Science Foundation Project Grant of $532,603 awarded to the Donald Danforth Plant Science Center on October 1, 2021 will fund research into the role of chloroplast signaling in regulating plasmodesmata. The goal is to identify chloroplast signals that change nuclear gene expression and define nuclear gene networks and signaling modules that alter plasmodesmata structure and function. The research will use reverse genetics, bioinformatics, molecular and biochemical approaches, and...
This $1,150,000 Project Grant award from the National Science Foundation's Biological Sciences (CFDA 47.074) program is supporting collaborative research by the Donald Danforth Plant Science Center to develop and share high-resolution in situ 3D cryo workflows to transform plant cell biology. The goal is to overcome challenges in cryogenic preservation of plant cells and tissues, allowing unprecedented observation of plant cell ultrastructure and organization in its native state using volume...
The National Science Foundation awarded a $179,150 Project Grant to the Donald Danforth Plant Science Center under the Biological Sciences federal grant program (CFDA 47.074) for the period of June 15, 2022 through May 31, 2024. The award will support the development of new computational tools and methods to translate single-cell RNA sequencing data into an ultra-high resolution 3D spatial map of gene expression in plant roots. Specifically, the grantee will leverage existing fluorescent...
This National Science Foundation (NSF) Project Grant award under the Biological Sciences (CFDA 47.074) program provides funding of $993,190 to the University of Maine System to conduct research focused on engineering stable, transmissible plant minichromosomes for synthetic biology applications. The project, titled "NSF-DBT: PLANTSYNBIO: PLANT MINICHROMOSOME ENGINEERING", aims to develop methods that expand the limits of plant minichromosome size, structure, and composition to create a...
This Project Grant from the National Science Foundation's Division of Molecular and Cellular Biosciences, under the Biological Sciences program (CFDA 47.074), provides $300,000 to the University of Kansas Center for Research Inc. from February 1, 2023 to January 31, 2025. The award will support research investigating delivery and trafficking of DNA introduced to cells from environmental sources using the genetically tractable organism Caenorhabditis elegans. The project aims to gain new...
The National Science Foundation awarded a $749,999 project grant to Texas A&M Agrilife Research from February 2021 through January 2025 under the Biological Sciences program (CFDA 47.074). The grant supports collaborative research on telomerase structure and evolution in photosynthetic eukaryotes. The Biological Sciences program aims to advance biological knowledge and enhance understanding of major problems through basic research. This award will further those goals by investigating...
The Salk Institute for Biological Studies was awarded a three-year, $881,161 Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) beginning July 1, 2021 to conduct research on Cross-Chiral Genetic Systems. The Biological Sciences program aims to promote advancement in the biological sciences and strengthen the national scientific enterprise through increasing knowledge and understanding of major problems. As part of this grant, The Salk Institute will...