Project Grant 2149172
Award Date
4/15/22
Completion Date
3/31/25
Dollars Obligated
$682K
Federal Agency
Division of Molecular and Cellular Biosciences
Federal Grant Program
47.074
Assistance Type
Project Grant
Place of Performance
Chapel Hill, NC 27599, USA
Similar Awards
This $366,624 National Science Foundation project grant supports collaborative research between Marshall University and the University of North Carolina at Chapel Hill to elucidate the molecular mechanisms governing cryptobiosis in tardigrades. Cryptobiosis refers to the unique ability of tardigrades, also known as water bears, to enter a suspended animation state called a "tun" that allows them to survive extreme environmental stressors. The investigators will combine proteomics,...
This $306,783 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences (CFDA 47.049) program will fund research by Appalachian State University to study the mechanism by which tardigrade-specific proteins can protect biomolecules from temperature-induced damage. The project aims to understand how tardigrades, also known as water bears, survive elevated temperatures, which could enable the development of more robust formulations for commercial...
The National Science Foundation (NSF) awarded a $378,347 Project Grant to Yale University to investigate the molecular mechanisms that allow tardigrades, a type of microorganism, to survive extreme environmental stresses such as desiccation, temperature, radiation, and pressure. The research under this CFDA 47.074 Biological Sciences program award aims to develop a detailed physiochemical understanding of the structure and function of tardigrade disordered proteins, which are believed to play...
The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $206,912 Project Grant under the Biological Sciences (CFDA 47.074) program to the University of North Carolina at Chapel Hill. The three-year grant, effective August 1, 2023 through July 31, 2026, supports collaborative research to enhance the understanding of protein structures and behaviors at extreme temperature and pressure conditions. The research aims to develop rules for predicting protein...
The National Science Foundation awarded a two-year, $138,000 Project Grant to support research titled "Neural Basis of Coordinated, Multi-Limbed Movement in an Emerging Model Tardigrade Species." The grant falls under the Biological Sciences program (CFDA 47.074), which aims to promote progress in the biological sciences and strengthen the nation's scientific enterprise through increasing knowledge and understanding of major problems. The grant will fund postdoctoral research from June...
This $795,135 Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports research at the University of Illinois on protein dynamics under extreme environmental conditions. The four-year award beginning June 1, 2022 will fund three related subprojects investigating how proteins adapt to enable organism survival in stressful environments like heat, pressure and dehydration. The research will study intrinsically disordered protein structure and...
The National Science Foundation awarded a $190,251 project grant to the University of North Carolina at Chapel Hill under the Biological Sciences program (CFDA 47.074) for research titled "COLLABORATIVE: ROL: MOLECULAR PATTERNS FOR REDOX SENSING AND SIGNALING IN ORGANISMIC DEFENSE." The grant period runs from August 1, 2021 through July 31, 2025. The research aims to advance understanding of major problems confronting the nation by promoting progress in the biological sciences....
This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Project Grant award to Syracuse University (SU) totaling $120,681 will fund collaborative research to understand how intrinsically disordered proteins provide desiccation protection across all kingdoms of life. The project will employ a multilevel, interdisciplinary approach, conducting in vitro and computational experiments at the molecular level, high-throughput sequencing studies in yeast at the cellular level, and...
The National Science Foundation (NSF) awarded a $750,000 Project Grant under the Biological Sciences program (CFDA 47.074) to the University of North Carolina at Chapel Hill (UNC-CH) to study the effects of macromolecular crowding on protein stability and interactions. The 3-year project will develop and test a new model for explaining how crowded cellular environments impact the free energy, enthalpy, and entropy of protein and protein complex stability. Key activities include using 19F NMR...
The National Science Foundation (NSF) awarded a $1,419,596 Project Grant under the Biological Sciences program (CFDA 47.074) to the University of North Carolina at Chapel Hill (UNC). The grant aims to identify the genetic basis of phenotypic plasticity - the ability of organisms to change their physical traits in response to environmental changes. Specifically, the research will study genetic variation underlying the spectacular carnivore larval morph in Mexican spadefoot toads, which is...