The National Science Foundation awarded Indiana University a $892,463 project grant under the Biological Sciences program (CFDA 47.074) for the period of April 1, 2022 through March 31, 2025. The grant funds the CAGEE project to develop new computational methods and open-source software for analyzing gene expression evolution across phylogenetic trees. The software will enable researchers to study changes in gene expression levels between tissues and species, and how such changes are coordinated on a genomic scale. It integrates statistical approaches to allow analysis of gene expression data from multiple platforms. The software package and associated research aims to advance understanding of gene expression changes responsible for differences between organisms and accelerate biological discoveries. The award also supports training of postdoctoral researchers, graduate students, and undergraduates from groups underrepresented in science and technology careers.
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