This $1,384,366 federal Project Grant award was provided by the National Science Foundation's Biological Sciences (CFDA 47.074) program to the University of California, Davis. The project aims to characterize the genome-wide epigenetic changes that occur during the transition from gametes to zygote in plants, with a focus on the important crop plant rice. The research will employ advanced techniques to isolate and analyze egg cells and zygotes, which has been challenging due to their limited...
The National Science Foundation awarded a two-year $299,986 Project Grant to the University of California, Davis under the Biological Sciences federal grant program (CFDA 47.074) from June 2023 to May 2025. The grant will support development of a new method to measure genome-wide targeting of histone readers, proteins that bind histone modifications to translate epigenetic codes into biological processes. If successful, the tool could help decipher how histones orchestrate genome and organism...
This $1,269,993 federal Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports research to understand the molecular basis of how plant cells establish the division plane during cell division. The project aims to dissect the function of cytoskeletal motor assemblies at the cortical division site and determine how they connect to molecules in the phragmoplast, the structure that forms the new cell wall during cytokinesis. Researchers at...
This Project Grant from the National Science Foundation Division of Integrative Organismal Systems, under the Biological Sciences federal grant program (CFDA 47.074), provides $298,102 to the University of California, Davis for research entitled "EAGER: Targeted and Specific Elimination of Plant Chromosomes." The two-year award beginning April 1, 2023 supports development of new genome editing techniques using CRISPR to enable targeted elimination of specific plant chromosomes at...
This Project Grant award from the National Science Foundation's Biological Sciences (CFDA 47.074) Federal Grant Program provides $279,922 to the University of California, Davis to develop new methods for generating diploid gametes in maize. The project aims to enable the inexpensive production of high-yielding hybrid maize seeds through asexual reproduction, which could have a significant impact on U.S. agriculture. The research approach involves editing multiple genes involved in cell...
The University of California, Davis (UC Davis) received a $389,525 federal Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) for a 5-year research project titled "CAREER: Mechanisms and Consequences of Epigenome-Recruited DNA Repair Systems in Plants." The project aims to study newly discovered DNA repair mechanisms in plants that could help protect critical genomic regions from harmful mutations. Researchers will leverage advanced...
This $999,999 Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) will fund research at the Donald Danforth Plant Science Center to elucidate the mechanisms initiating de novo chromatin modification cycles in plant cells. Over three years, the award will support experiments using cutting-edge techniques to dissect the molecular triggers establishing heritable DNA methylation patterns and long-term epigenetic silencing of transposable elements and...
The National Science Foundation awarded the University of California, Davis a $981,302 Project Grant under the Biological Sciences federal grant program (CFDA 47.074) on May 15, 2022 to complete the project by April 30, 2026. The grant will support research aimed at understanding the molecular mechanisms governing cytoskeleton-mediated motility and distribution of peroxisomes and mitochondria in plants. Specifically, the university researchers will investigate the roles of candidate proteins...
The University of California, Davis (UC Davis) has been awarded a $300,000 EAGER (Early-concept Grants for Exploratory Research) grant from the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences. The grant supports a project to investigate the use of CRISPR gene editing technology to separate closely linked beneficial and harmful traits in plants. Specifically, the project aims to determine whether eliminating certain DNA repair pathways, such as the Ku-dependent...
The National Science Foundation Division of Integrative Organismal Systems awarded a $206,320 Project Grant to the Donald Danforth Plant Science Center for the period of May 1, 2022 through April 30, 2023. The grant supports collaborative research to develop an artificial chromosome system in Chlamydomonas based on CENH3 tethering under the Biological Sciences program (CFDA 47.074). The Biological Sciences program aims to promote progress in the biological sciences and strengthen the nation's...