Project Grant 2126989
Award Date
7/15/21
Completion Date
6/30/23
Dollars Obligated
$256K
Federal Agency
National Science Foundation
Federal Grant Program
47.084
Assistance Type
Project Grant
Place of Performance
Marshallton, DE 19808, USA
Similar Awards
This National Science Foundation (NSF) Small Business Innovation Research (SBIR) Phase I award to Bactria Pharmaceuticals LLC is providing $274,937 to develop therapeutic drugs that restore antibiotic sensitivity in bacteria that cause severe healthcare-associated infections. The goal is to combat antimicrobial resistance in gram-negative pathogens through the use of small molecule efflux pump inhibitors (EPIs). The project involves three key activities: cryo-electron microscopy to understand...
Felix Biotechnology Inc. received a $256,000 Small Business Innovation Research Phase I Project Grant from the National Science Foundation under the NSF Technology, Innovation, and Partnerships program. The 12-month project aims to leverage machine learning techniques to enable generalized phage therapy for pulmonary infections. Phage therapy utilizes bacteriophages, or viruses that infect bacteria, as an alternative to traditional antibiotics. This award will support Felix Biotechnology's...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $273,652 to Phage Refinery LLC aims to develop a rapid and efficient parametric model for predicting the likelihood that a given bacteriophage (phage) will survive sufficiently long in the presence of an active immune system to be effective as a treatment against their target bacterial infection. The project will gather physical parameters and in-vivo persistence data for 400...
This $275,000 Small Business Innovation Research (SBIR) Phase I project, awarded by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program, aims to develop improved bacterial strains for the productive secretion of difficult-to-express proteins through precision fermentation. The project seeks to identify superior bacterial protein production hosts and develop genetic tools and methodologies to convert these hosts into efficient protein...
This $305,000 Project Grant was awarded on March 1, 2025 by the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084). The grant was awarded to Resonantia Diagnostics, Inc., a for-profit, veteran-owned small business located in Durham, North Carolina. The objective of this SBIR Phase I project is to develop a transformative diagnostic platform capable of rapidly identifying pathogens and determining their antimicrobial susceptibility...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 aims to develop a platform for detecting genetic antibiotic resistance motifs that can predict current and future susceptibility to therapeutics. The project will establish the feasibility of leveraging mutational signatures in bacterial DNA to identify antibiotic resistance status, including the potential for rapid development of multi-drug resistance. This approach...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Phase I Small Business Innovation Research (SBIR) grant awarded to Multitarga LLC for $304,995 will develop an "adaptive multi-targeted priming" technology to enhance the detection of low-abundance pathogen transcripts in complex host-pathogen samples. The project, titled "Adaptive Multi-Targeted Priming for Host-Pathogen Transcriptomics: Leveraging Graph Representation Learning for...
This SBIR Phase I award from the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $273,550 to Biocognon LLC for the development of a combinatorial platform to discover improved molecular recognition components for use in therapeutic and diagnostic antibodies. The project aims to utilize synthetic biology, next-generation DNA sequencing, and computational biology to efficiently generate and screen libraries of antibody...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $305,000 to Novaurum Biosciences Incorporated supports the development of a novel mammalian cell-based nano-biological coating for implantable medical devices. The key objectives are to: (1) characterize nanoparticles produced by different cells on orthopedic implant materials, (2) determine the antibacterial, anti-inflammatory, and cell proliferation properties of the coated...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Cooperative Agreement award of $984,381 to Cobio Diagnostics Inc. in Aurora, Colorado aims to expand a diagnostic tool that enables rapid, direct-from-specimen identification and antimicrobial susceptibility testing of major bloodborne bacterial pathogens. The project will develop a regulatory pathway for FDA clearance, characterize antibodies to expand the test, and validate the expanded tests...