Project Grant 2126731
Award Date 9/1/21
Completion Date 8/31/22
Dollars Obligated $256K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
South San Francisco, CA 94080, USA
Similar Awards
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $273,652 to Phage Refinery LLC aims to develop a rapid and efficient parametric model for predicting the likelihood that a given bacteriophage (phage) will survive sufficiently long in the presence of an active immune system to be effective as a treatment against their target bacterial infection. The project will gather physical parameters and in-vivo persistence data for 400...
- The National Science Foundation awarded Ancilia, Inc. a $255,717 Small Business Technology Transfer Phase I Project Grant under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084). The grant will support development of phage-resistant bacterial therapeutics from July 2021 through June 2023. The NSF Technology, Innovation, and Partnerships program seeks to advance science, engineering, and technology innovation to address national challenges. Under this award, Ancilia...
- This National Science Foundation (NSF) Small Business Innovation Research (SBIR) Phase I award to Bactria Pharmaceuticals LLC is providing $274,937 to develop therapeutic drugs that restore antibiotic sensitivity in bacteria that cause severe healthcare-associated infections. The goal is to combat antimicrobial resistance in gram-negative pathogens through the use of small molecule efflux pump inhibitors (EPIs). The project involves three key activities: cryo-electron microscopy to understand...
- Vulcan Biologics Inc. received a $989,854 cooperative agreement award from the National Science Foundation Division of Industrial Innovation under the Engineering federal grant program (CFDA 47.041) to support the development of a bacteriophage-based microbial gene therapy platform for in situ engineering of microbiomes. This project will leverage bacteriophages to deliver targeted genetic modifications within complex microbial communities, with the goal of engineering the function and...
- Cobio Diagnostics Inc. received a $256,000 Project Grant award from the National Science Foundation on April 1, 2021 to support work concluding on March 31, 2022. The grant was awarded under the NSF's Engineering program (CFDA 47.041), which aims to improve quality of life and economic strength through engineering research and education. Specifically, the grant funds Cobio Diagnostics' "SBIR PHASE I: PHAGE-AMPLIFIED IDENTIFICATION AND ANTIMICROBIAL SUSCEPTIBILITY TEST" project. This...
- This SBIR Phase I award from the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $273,550 to Biocognon LLC for the development of a combinatorial platform to discover improved molecular recognition components for use in therapeutic and diagnostic antibodies. The project aims to utilize synthetic biology, next-generation DNA sequencing, and computational biology to efficiently generate and screen libraries of antibody...
- This $274,797 National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award to Deepseq.ai LLC supports the development of an AI-driven platform to accelerate the identification of highly developable single-domain antibodies for drug discovery. The proposed work aims to create a multimodal AI model capable of rapidly screening large libraries to generate lead molecules with favorable binding affinity, stability, and manufacturability. This project...
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Cooperative Agreement award of $984,381 to Cobio Diagnostics Inc. in Aurora, Colorado aims to expand a diagnostic tool that enables rapid, direct-from-specimen identification and antimicrobial susceptibility testing of major bloodborne bacterial pathogens. The project will develop a regulatory pathway for FDA clearance, characterize antibodies to expand the test, and validate the expanded tests...
- This National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) Project Grant award of $240,000 will fund a 3-year postdoctoral fellowship to research the adaptive response of bacteria to bacteriophage infection and high hydrostatic pressure. The fellow will develop novel fluorescence microscopy techniques to quantify bacterial growth, cell size, and morphology under these environmental stressors using model organisms E. coli, P. aeruginosa, and S. piezotolerans. The project...
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Om Therapeutics Inc. will support the development of a system to enable the rapid, scalable, and cost-effective discovery of new medicines using machine learning. The project aims to encapsulate proteins and small molecules in millions of miniaturized compartments to screen for interactions that could identify novel drug candidates. The key innovations include...